Catalysis

Ketone

Magnesium

Combinatorial chemistry

Organic chemistry

Mathematics

Chemoselectivity

Geometry

Chemistry

Reaction conditions

Reduction (mathematics)

Organic Letters

The chemoselective reduction of α,β-unsaturated ketones by use of an economic and readily available Mg catalyst has been developed. Excellent yields for a wide range of ketones have been achieved under mild reaction conditions, short times, and low catalyst loadings (0.2-0.5 mol %).

Chemoselective Luche-Type Reduction of α,β-Unsaturated Ketones by Magnesium Catalysis