extraction yield

aqueous two-phase

deep eutectic solvent

supercritical fluid

extraction conditions

solvent extraction

liquid liquid

pectin

extraction time

microwave-assisted extraction

Journal of Cleaner Production

Green extraction processes to obtain high value bioactive compounds from raw natural materials and wastes has gained attention the past few years. In the present study, we investigated a Natural Deep Eutectic Solvent derived from two natural products, namely choline chloride and L(+)-tartaric acid as a potential solvent for the extraction of phenolic compounds from Greek propolis and carotenoids from apricot and shrimp wastes. High energy techniques were used in combination with the NaDES in order to minimize the extraction time and maximize the yield. Two- and three-level experimental design was implemented in order to statistically investigate the correlation between the extraction conditions and the obtained extracts and find the optimum conditions. The proposed methodology resulted in the efficient extraction of the desired bioactive compounds despite their different structure and polarity. The optimized process could be considered as a competitive alternative to conventional processes.

Choline chloride and tartaric acid, a Natural Deep Eutectic Solvent for the efficient extraction of phenolic and carotenoid compounds