Physics

Internal medicine

Mathematics

Nuclear magnetic resonance spectroscopy

Statistics

Multivariate statistics

Materials science

Spectroscopy

Multivariate analysis

Nuclear magnetic resonance

Quantum mechanics

Medicine

TrAC Trends in Analytical Chemistry

Lipoproteins and their subfraction profiles have been associated to diverse diseases including Cardio Vascular Disease (CVD).There is thus a great demand for measuring and quantifying the lipoprotein profile in an efficient and accurate manner.Nuclear Magnetic Resonance (NMR) spectroscopy is uniquely able to measure the lipoprotein profile of a blood sample non-destructively due to its sensitivity to both lipid chemistry and lipid-micellar physics.However, the NMR spectra must be scaled/regressed to a primary method of reference, such as ultracentrifugation, using multivariate regression methods.This review provides an overview of the field and explains the methods at stake.

Corrigendum to “Quantification of lipoprotein profiles by nuclear magnetic resonance spectroscopy and multivariate data analysis” [Trends Anal Chem 94 (2017) 210–219]