Electrical engineering

Public health

Pathology

Dipeptidyl peptidase-4

Middle East respiratory syndrome coronavirus

Disease

Coronavirus disease 2019 (COVID-19)

Infectious disease (medical specialty)

Diabetes mellitus

Endocrinology

Engineering

Virology

Type 2 diabetes

Betacoronavirus

Middle East respiratory syndrome

Coronavirus

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Medicine

Transmission (telecommunications)

GERMS

As a novel coronavirus first reported by Saudi Arabia in 2012, the Middle East respiratory syndrome coronavirus (MERS-CoV) is responsible for an acute human respiratory syndrome.The virus, of 2C beta-CoV lineage, expresses the dipeptidyl peptidase 4 (DPP4) receptor and is densely endemic in dromedary camels of East Africa and the Arabian Peninsula.MERS-CoV is zoonotic but human-to-human transmission is also possible.Surveillance and phylogenetic researches indicate MERS-CoV to be closely associated with bats' coronaviruses, suggesting bats as reservoirs, although unconfirmed.With no vaccine currently available for MERS-CoV nor approved prophylactics, its global spread to over 25 countries with high fatalities highlights its role as ongoing public health threat.An articulated action plan ought to be taken, preferably from a One Health perspective, for appropriately advanced countermeasures against MERS-CoV.

Middle East respiratory syndrome coronavirus (MERS-CoV): A review