Review paper

Principles of genome folding into topologically associating domains

Volume: 5, Issue: 4
Published: Apr 5, 2019
Abstract
Understanding the mechanisms that underlie chromosome folding within cell nuclei is essential to determine the relationship between genome structure and function. The recent application of "chromosome conformation capture" techniques has revealed that the genome of many species is organized into domains of preferential internal chromatin interactions called "topologically associating domains" (TADs). This chromosome chromosome folding has...
Paper Details
Title
Principles of genome folding into topologically associating domains
Published Date
Apr 5, 2019
Volume
5
Issue
4
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