Transcription factor

Biology

Gene

Biogenesis

Gene silencing

Gene expression

RNA interference

microRNA

RNA-induced silencing complex

Non-coding RNA

Regulation of gene expression

Argonaute

Computational biology

Cell biology

Genetics

Frontiers in Plant Science

MicroRNAs (miRNAs), a class of endogenous, tiny, non-coding RNAs, are master regulators of gene expression among most eukaryotes. Intracellular miRNA abundance is regulated under multiple levels of control including transcription, processing, RNA modification, RNA-induced silencing complex (RISC) assembly, miRNA-target interaction, and turnover. In this review, we summarize our current understanding of the molecular components and mechanisms that influence miRNA biogenesis, homeostasis, and degradation in plants. We also make comparisons with findings from other organisms where necessary.

Plant microRNAs: Biogenesis, Homeostasis, and Degradation