Catalysis

Medicinal chemistry

Combinatorial chemistry

Physics

Organic chemistry

Astronomy

Propargyl

Primary (astronomy)

Chemistry

Organic Letters

By using silver complexes with bulky ligands such as DavePhos or N-heterocyclic carbenes, propargylic alcohols are smoothly converted with CO2 into a unique class of unexplored cyclic alkylidene carbonates. These systems, for the first time, also achieve the direct carboxylative cyclization of primary propargylic alcohols. The silver-DavePhos catalyst is further applied for the bis-carboxylative cyclization of primary propargyl derivatives, thereby providing an effective route to a series of previously inaccessible and industrially relevant α-alkylidene cyclic carbonates.

Silver-Catalyzed Carboxylative Cyclization of Primary Propargyl Alcohols with CO<sub>2</sub>

Silver-Catalyzed Carboxylative Cyclization of Primary Propargyl Alcohols with CO2

Silver-Catalyzed Carboxylative Cyclization of Primary Propargyl Alcohols with CO₂