Ecology

Biology

Biochemistry

Botany

Stereochemistry

Triterpenoid

Cytotoxicity

Genetics

In vitro

Meliaceae

Bark (sound)

Cytotoxic T cell

Cancer cell lines

Medicine

Chemistry

Cancer

Traditional medicine

Cancer cell

Phytochemistry Letters

Four new triterpenoids, namely, chisopaten A-D (1-4), were isolated from the n-hexane extract of the bark of Chisocheton patens Blume. The chemical structures of new compounds were elucidated on the basis of spectroscopic data interpretation. All isolated compounds were evaluated for their cytotoxic activity against MCF-7 breast cancer lines. Chisopaten A and C, showed strongest cytotoxicity activity with IC50 values of 4.01 ± 0.008 and 4.33 ± 0.009 μM, respectively.

Cytotoxic Triterpenoids from the Bark of Chisocheton patens Blume (Meliaceae)