Internal medicine

Sociology

Family history

Population

Cancer

Risk assessment

Demography

Computer science

Breast cancer

Computer security

Medicine

Environmental health

Genetics in Medicine

Breast cancer (BC) risk prediction allows systematic identification of individuals at highest and lowest risk. We extend the Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) risk model to incorporate the effects of polygenic risk scores (PRS) and other risk factors (RFs).

BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors