Polymer–drug conjugate therapeutics: advances, insights and prospects
Abstract
Polymer–drug conjugates have long been a mainstay of the drug delivery field, with several conjugates successfully translated into clinical practice. The conjugation of therapeutic agents to polymeric carriers, such as polyethylene glycol, offers several advantages, including improved drug solubilization, prolonged circulation, reduced immunogenicity, controlled release and enhanced safety. In this Review, we discuss the rational design,...
Paper Details
Title
Polymer–drug conjugate therapeutics: advances, insights and prospects
Published Date
Dec 12, 2018
Volume
18
Issue
4
Pages
273 - 294
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