Intensive care medicine

Malaria

Anemia

Malnutrition

Immunology

Pediatrics

Sickle cell anemia

Hemolytic anemia

Hemoglobinopathy

Internal medicine

Medicine

Disease

New England Journal of Medicine

Hydroxyurea is an effective treatment for sickle cell anemia, but few studies have been conducted in sub-Saharan Africa, where the burden is greatest. Coexisting conditions such as malnutrition and malaria may affect the feasibility, safety, and benefits of hydroxyurea in low-resource settings.

Hydroxyurea for Children with Sickle Cell Anemia in Sub-Saharan Africa