Original paper
RB1 Heterogeneity in Advanced Metastatic Castration-Resistant Prostate Cancer
Abstract
Purpose: Metastatic castration-resistant prostate cancer (mCRPC) is a lethal but clinically heterogeneous disease, with patients having variable benefit from endocrine and cytotoxic treatments. Intrapatient genomic heterogeneity could be a contributing factor to this clinical heterogeneity. Here, we used whole-genome sequencing (WGS) to investigate genomic heterogeneity in 21 previously treated CRPC metastases from 10 patients to investigate...
Paper Details
Title
RB1 Heterogeneity in Advanced Metastatic Castration-Resistant Prostate Cancer
Published Date
Jan 15, 2019
Journal
Volume
25
Issue
2
Pages
687 - 697
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Notes
History