Gene

Bubble

World Wide Web

Biology

Visualization

Open source

Web application

Data mining

Parallel computing

Computer science

Computational biology

Maximum bubble pressure method

Software

Genetics

Genome

Interface (matter)

Interactive visualization

Modalities

Sociology

Genomics

Data science

Genome browser

Data visualization

Programming language

Human–computer interaction

Social science

Genome biology

We present HiGlass, an open source visualization tool built on web technologies that provides a rich interface for rapid, multiplex, and multiscale navigation of 2D genomic maps alongside 1D genomic tracks, allowing users to combine various data types, synchronize multiple visualization modalities, and share fully customizable views with others. We demonstrate its utility in exploring different experimental conditions, comparing the results of analyses, and creating interactive snapshots to share with collaborators and the broader public. HiGlass is accessible online at http://higlass.io and is also available as a containerized application that can be run on any platform.

HiGlass: web-based visual exploration and analysis of genome interaction maps