Pathology

Tuberculosis

Programming language

Isoniazid

Side effect (computer science)

Computer science

Medicine

New England Journal of Medicine

The treatment of latent infection with Mycobacterium tuberculosis is important in children because of their vulnerability to life-threatening forms of tuberculosis disease. The current standard treatment — 9 months of isoniazid — has been associated with poor adherence and toxic effects, which have hampered the effectiveness of the drug. In adults, treatment with 4 months of rifampin has been shown to be safer and to have higher completion rates than 9 months of isoniazid.

Safety and Side Effects of Rifampin versus Isoniazid in Children