Silane

Materials science

Archaeology

Milestone

Combinatorial chemistry

Nanotechnology

Organic chemistry

Reagent

Trimethylsilyl

Chemistry

History

Chemical Reviews

This review is an update on tris(trimethylsilyl)silane, TTMSS, in organic chemistry, focusing on the advancements of the past decade. The overview includes a wide range of chemical processes and synthetic strategies under different experimental conditions, including functional group insertion and transformations, as well as preparation of complex molecules, natural products, polymers, surfaces, and new materials. These results reveal how TTMSS has matured over the past 30 years, and they further establish its value as a free radical reagent with widespread academic and industrial applications.

Thirty Years of (TMS)<sub>3</sub>SiH: A Milestone in Radical-Based Synthetic Chemistry

Thirty Years of (TMS)3SiH: A Milestone in Radical-Based Synthetic Chemistry

Thirty Years of (TMS)₃SiH: A Milestone in Radical-Based Synthetic Chemistry