Organic chemistry

Combinatorial chemistry

Allene

Reagent

Catalysis

Stoichiometry

Natural rubber

Intermolecular force

Chemistry

Imine

Enyne

Diene

Molecule

Chemical Reviews

Metal-catalyzed reductive coupling has emerged as an alternative to the use of stoichiometric organometallic reagents in an increasingly diverse range of carbonyl and imine additions. In this review, the use of diene, allene, and enyne pronucleophiles in intermolecular carbonyl and imine reductive couplings are surveyed, along with related hydrogen autotransfer processes.

Intermolecular Metal-Catalyzed Reductive Coupling of Dienes, Allenes, and Enynes with Carbonyl Compounds and Imines