vitamin D deficiency

Colorectal cancer

Endocrinology

Relative risk

Internal medicine

Confidence interval

Epidemiology

Vitamin D and neurology

Medicine

Gastroenterology

Cancer

JNCI Journal of the National Cancer Institute

Experimental and epidemiological studies suggest a protective role for vitamin D in colorectal carcinogenesis, but evidence is inconclusive. Circulating 25-hydroxyvitamin D (25(OH)D) concentrations that minimize risk are unknown. Current Institute of Medicine (IOM) vitamin D guidance is based solely on bone health.

Circulating Vitamin D and Colorectal Cancer Risk: An International Pooling Project of 17 Cohorts