Psychological intervention

Gene

World Wide Web

Malaria

Biology

Parasite hosting

Malarial parasites

Psychiatry

Biochemistry

Computer science

Vector (molecular biology)

Plasmodium falciparum

Immunology

Plasmodium (life cycle)

Disease Eradication

Artificial intelligence

Medicine

Perspective (graphical)

Disease

Recombinant DNA

Pathology

American Journal of Tropical Medicine and Hygiene

Important strides have been made within the past decade toward malaria elimination in many regions, and with this progress, the feasibility of eradication is once again under discussion. If the ambitious goal of eradication is to be achieved by 2040, all species of Plasmodium infecting humans will need to be targeted with evidence-based and concerted interventions. In this perspective, the potential barriers to achieving global malaria elimination are discussed with respect to the related diversities in host, parasite, and vector populations. We argue that control strategies need to be reorientated from a sequential attack on each species, dominated by Plasmodium falciparum to one that targets all species in parallel. A set of research themes is proposed to mitigate the potential setbacks on the pathway to a malaria-free world.

Malaria Elimination: Time to Target All Species