Differences in the Electrophysiological Properties of Mouse Somatosensory Layer 2/3 NeuronsIn Vivoand Slice Stem from Intrinsic Sources Rather than a Network-Generated High Conductance State
Abstract
Synaptic activity in vivo can potentially alter the integration properties of neurons. Using recordings in awake mice, we targeted somatosensory layer 2/3 pyramidal neurons and compared neuronal properties with those from slices. Pyramidal cells in vivo had lower resistance and gain values, as well as broader spikes and increased spike frequency adaptation compared to the same cells in slices. Increasing conductance in neurons using dynamic...
Paper Details
Title
Differences in the Electrophysiological Properties of Mouse Somatosensory Layer 2/3 NeuronsIn Vivoand Slice Stem from Intrinsic Sources Rather than a Network-Generated High Conductance State
Published Date
Mar 1, 2018
Journal
Volume
5
Issue
2
Pages
ENEURO.0447 - 17.2018
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