Internal medicine

Radiology

Pathology

Stereotactic biopsy

Lymphoma

Primary central nervous system lymphoma

Central nervous system

Medical history

Biopsy

Cerebrospinal fluid

Dysarthria

Past medical history

Medicine

Journal of Clinical Neuroscience

Primary central nervous system lymphoma (PCNSL) is an aggressive malignancy tumor which represents about 1%-2% of all non-Hodgkin lymphomas and 2%-6% of all brain tumors [1–4]. It exclusively involves the central nervous system, including the brain, spinal cord, eyes, meninges and cranial nerves [5]. The spinal involvement is very rare and only a small number of cases were reported in literature [3,6–8]. Population aged 50–65 years old is especially vulnerable to PCNSL, which is diversified in clinical presentation and image characters [9,10].

Spinal primary central nervous system lymphoma: Case report and literature review