Broad spectrum

Nitrogen atom

Biology

Materials science

Isoxazole

Molecule

Computational biology

Stereochemistry

Combinatorial chemistry

Oxygen atom

Nanotechnology

Organic chemistry

Chemistry

Ring (chemistry)

Medicinal Chemistry Research

Isoxazole, constituting an important family of five-membered heterocycles with one oxygen atom and one nitrogen atom at adjacent positions is of immense importance because of its wide spectrum of biological activities and therapeutic potential. It is, therefore, of prime importance that the development of new synthetic strategies and designing of new isoxazole derivatives should be based on the most recent knowledge emerging from the latest research. This review is an endeavor to highlight the progress in the chemistry and biological activity of isoxazole derivatives which could provide a low-height flying bird’s eye view of isoxazole derivatives to the medicinal chemists for the development of clinically viable drugs using this information.

The synthetic and therapeutic expedition of isoxazole and its analogs