A new fluorescence turn-on nanobiosensor for the detection of micro-RNA-21 based on a DNA–gold nanocluster

Volume: 5, Issue: 1, Pages: 015005 - 015005
Published: Mar 8, 2017
Abstract
In this study, DNA/gold nanoclusters (AuNCs) were used to develop an AuNC-based turn-on fluorescence probe for the analysis of mi-RNA-21, which is a potential screening biomarker for cancer detection. AuNCs on a DNA scaffold were prepared through a one-pot wet-chemical route and evaluated by transmission electron microscopy and dynamic light scattering. Experiments revealed that the fluorescence intensity of the DNA-AuNCs showed a gradual...
Paper Details
Title
A new fluorescence turn-on nanobiosensor for the detection of micro-RNA-21 based on a DNA–gold nanocluster
Published Date
Mar 8, 2017
Volume
5
Issue
1
Pages
015005 - 015005
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