Structure and function of carbonic anhydrases
Abstract
Carbonic anhydrases (CAs, EC 4.2.1.1) catalyse the interconversion between CO2 and bicarbonate as well as other hydrolytic reactions. Among the six genetic families known to date, the α-, β-, γ-, δ-, ζ- and η-CAs, detailed kinetic and X-ray crystallographic studies have allowed a deep understanding of the structure-function relationship in this superfamily of proteins. A metal hydroxide nucleophilic species of the enzyme, and a unique active...
Paper Details
Title
Structure and function of carbonic anhydrases
Published Date
Jul 12, 2016
Journal
Volume
473
Issue
14
Pages
2023 - 2032
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