[Progress in studies of mechanism of anti-fibrosis traditional Chinese drugs and effective components].

Published on Dec 1, 2008in China journal of Chinese materia medica
Shu-Jun Sun2
Estimated H-index: 2
,
Yang Xiang2
Estimated H-index: 2
,
Shi-Lin Huang2
Estimated H-index: 2
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Abstract
The progress in the research of pharmacological mechanism of anti-fibrosis traditional Chinese drugs and the effective components is summarized.It's demonstrated by pharmacological experiments that anti-fibrosis traditional Chinese drugs can inhibit the cell proliferation,regulate the cytokines and ECM,and intervente in the signal transduction.
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Traditional herbal medicine is usually administrated according to experiences and practices. We aimed to investigate the anti-fibrotic effects of Shenqi Neijin powder (SQNJP) in hepatic fibrosis rats induced by carbon tetrachloride (CCl4). A total of 32 rats were divided into control group, model group, and SQNJP group. The hydroxyproline content was assayed. Histological features of liver tissues were determined with different staining methods. Western blotting analysis and immuno-fluorescence ...
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#1Hong-dong XieH-Index: 1
#2Wei HouH-Index: 1
Last. Juanjuan MaoH-Index: 1
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Traditional herbal medicine is usually administrated according to experiences and practices. We aimed to investigate the anti-fibrotic effects of Shenqi Neijin powder (SQNJP) in hepatic fibrosis rats induced by carbon tetrachloride (CCl4). A total of 32 rats were divided into control group, model group, and SQNJP group. The hydroxy- proline content was assayed. Histological features of liver tissues were determined with different staining methods. Western blotting analysis and immuno-fluorescenc...