Original paper
Crucial roles of XCR1-expressing dendritic cells and the XCR1-XCL1 chemokine axis in intestinal immune homeostasis
Abstract
Intestinal immune homeostasis requires dynamic crosstalk between innate and adaptive immune cells. Dendritic cells (DCs) exist as multiple phenotypically and functionally distinct sub-populations within tissues, where they initiate immune responses and promote homeostasis. In the gut, there exists a minor DC subset defined as CD103 + CD11b − that also expresses the chemokine receptor XCR1. In other tissues, XCR1 + DCs cross-present antigen and...
Paper Details
Title
Crucial roles of XCR1-expressing dendritic cells and the XCR1-XCL1 chemokine axis in intestinal immune homeostasis
Published Date
Mar 23, 2016
Journal
Volume
6
Issue
1
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Notes
History