Impact of topical application of sulfur mustard on mice skin and distant organs DNA repair enzyme signature
Abstract
Sulfur mustard (SM) is a chemical warfare agent that, upon topical application, damages skin and reaches internal organs through diffusion in blood. Two major toxic consequences of SM exposure are inflammation, associated with oxidative stress, and the formation of alkylated DNA bases. In the present study, we investigated the impact of exposure to SM on DNA repair, using two different functional DNA repair assays which provide information on...
Paper Details
Title
Impact of topical application of sulfur mustard on mice skin and distant organs DNA repair enzyme signature
Published Date
Jan 1, 2016
Journal
Volume
241
Pages
71 - 81
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