Medicine

Chemistry

Traditional medicine

Journal of Medicinal Plants Research

Crude methanolic extracts of the aerial part of the two Laggera species (Laggera pterodonta (DC.) Sch. Bip. and Laggera aurita (Linn f.) DC.) from the family Asteraceae (Compositea), found in Nigeria were screened againstMycobacterial bovis (BCG strains). The two extracts were found to be active at minimum inhibitory concentrations (MIC) of 625 µg/ml. Further fractionation and screening of the fractions against BCG shows moderate activity for some of the fractions. The four compounds (crystals) isolated in the process did not show any activity, but are currently being analyzed by spectroscopy for characterization and identification.	 	Key words: Laggera pterodonta, Laggera aurita, anti-tuberculosis.

Preliminary anti-tuberculosis screening of two Nigerian Laggera species (Laggera pterodonta and Laggera aurita)