Timolol

Propranolol

Glaucoma

Intraocular pressure

Ophthalmology

Surgery

Ocular hypertension

Sturge–Weber syndrome

Anesthesia

Medicine

European Journal of Ophthalmology

To report the effect of oral propranolol on intraocular pressure (IOP) in infants newly diagnosed with unilateral Sturge-Weber syndrome (SWS) glaucoma receiving no other treatment.This was a prospective, nonrandomized interventional case series. Four infants presenting with unilateral SWS glaucoma with no prior treatment were treated with oral propranolol at a dose of 2 mg/kg and followed thereafter.Propranolol had a temporary IOP-lowering effect in 3 of 4 children after 1 week of treatment. This effect diminished thereafter and 3 of 4 children required additional medical or surgical treatment.Oral propranolol has a temporary effect on IOP in SWS glaucoma and is not effective as a single treatment in this syndrome, yet can serve to delay surgical treatment for a short period of time. In one case, the glaucoma was well-controlled on this medication.

The Effect of Oral Propranolol on Intraocular Pressure in Infants with Sturge-Weber Syndrome Glaucoma