Fast and accurate short read alignment with Burrows–Wheeler transform

Bioinformatics
6.94
Volume: 25, Issue: 14, Pages: 1754 - 1760
Published: Jul 1, 2009

Abstract
Motivation: The enormous amount of short reads generated by the new DNA sequencing technologies call for the development of fast and accurate read alignment programs. A first generation of hash table-based methods has been developed, including MAQ, which is accurate, feature rich and fast enough to align short reads from a single individual. However, MAQ does not support gapped alignment for single-end reads, which makes it unsuitable for...


Paper Details
Title
Fast and accurate short read alignment with Burrows–Wheeler transform
DOI
Published Date
1 Jul, 2009
Journal
Volume
25
Issue
14
Pages
1754 - 1760
Trends
Citation Distributions