Catalysis

Enantioselective synthesis

Receptor

Biochemistry

Combinatorial chemistry

Ligand (biochemistry)

Organic chemistry

Asymmetric hydrogenation

Chemistry

Iridium

Chiral ligand

Organic Letters

New Ir−SimplePHOX complexes Ir-6−Ir-9 catalyze the quantitative, highly enantioselective hydrogenation of a range of unfunctionalized and functionalized olefins. Synthesis, catalytic results, and X-ray crystal structures are presented here.

SimplePHOX, a Readily Available Chiral Ligand System for Iridium-Catalyzed Asymmetric Hydrogenation