Nuclear chemistry

Catalysis

Antimicrobial

Potassium hydroxide

Claisen condensation

Combinatorial chemistry

Organic chemistry

Coumarin

Proton NMR

Aldehyde

Medicine

Chemistry

Ethanol

Piperidine

Traditional medicine

Journal of Chemistry

Five novel chalcones were synthesised by condensing 2‐hydroxy‐1‐acetonaphthone with aldehyde derivatives in dilute ethanolic potassium hydroxide solution at room temperature according to Claisen‐Schmidt condensation and another five novel chalcones were prepared by refluxing 3‐acetyl coumarin with aldehydes in the presence of piperidine in ethanol. All these compounds were characterised by means of their IR, 1 H NMR spectroscopic data and microanalyses. The antimicrobial activity of these compounds were evaluated by the cup plate method.

Synthesis and Antimicrobial Activity of Some Novel Chalcones of 2-Hydroxy -1-Acetonapthone and 3-Acetyl Coumarin