Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity
Abstract
Toll-like receptors (TLRs) are germline-encoded pattern recognition receptors (PRRs) that play a central role in host cell recognition and responses to microbial pathogens. TLR-mediated recognition of components derived from a wide range of pathogens and their role in the subsequent initiation of innate immune responses is widely accepted; however, the recent discovery of non-TLR PRRs, such as C-type lectin receptors, NOD-like receptors, and...
Paper Details
Title
Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity
Published Date
May 1, 2011
Journal
Volume
34
Issue
5
Pages
637 - 650
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