Immunohistochemical evaluation of parathyroid hormone-related protein (PTHrP) in the uterine cervix

We investigated the immunohistochemical localization of parathyroid hormone‐related protein (PTHrP), a major factor responsible for the humoral hypercalcemia of malignancy, in uterine cervical lesions. Formalin‐fixed paraffin‐embedded specimens from 16 cases of normal and reactive conditions, 45 cases of cervical intra‐epithelial neoplasm (CIN) and 63 cases of invasive cancer were studied immunohistochemically by the avidine‐biotin‐peroxidase...