Primary cilia regulate mTORC1 activity and cell size through Lkb1
Abstract
The mTOR pathway is a well-known regulator of cell size, and deregulation of mTOR has been observed in cilia-related diseases. Cilia modulate cell size by restricting LKB-1-mediated activation of AMPK to the basal body, which subsequently affects mTOR...
Paper Details
Title
Primary cilia regulate mTORC1 activity and cell size through Lkb1
Published Date
Nov 1, 2010
Journal
Volume
12
Issue
11
Pages
1115 - 1122
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