Hepatology International
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#1George K. K. LauH-Index: 79
#1George Lau (Chinese PLA General Hospital)H-Index: 6
Last. Gregory Cheng (Chinese PLA General Hospital)
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BACKGROUND & AIM Hepatitis B reactivation related to the use of immunosuppressive therapy remains a major cause of liver-related morbidity and mortality in hepatitis B endemic Asia-Pacific region. This clinical practice guidelines aim to assist clinicians in all disciplines involved in the use of immunosuppressive therapy to effectively prevent and manage hepatitis B reactivation. METHODS All publications related to hepatitis B reactivation with the use of immunosuppressive therapy since 1975 we...
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#1Takayuki Shimizu (Dokkyo Medical University)H-Index: 9
#2Taku Aoki (Dokkyo Medical University)H-Index: 38
Last. Keiichi Kubota (Dokkyo Medical University)H-Index: 60
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AIM Indocyanine green retention rate at 15 min (ICGR15) is a frequently used indicator of liver function. Herein, clinicopathological characteristics of cirrhotic patients with normal ICGR15 value ( 10% (Group C, n = 296). Background characteristics and surgical outcomes were compared between groups. Functional liver volume (FLV) was computed using total liver volume and signal intensity ratio. Liver parenchymal cell volume ratio was measured in non-cancerous tissue obtained from resected specim...
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#1Cheng Han Ng (NUS: National University of Singapore)H-Index: 6
#2Darren Jun Hao Tan (NUS: National University of Singapore)
Last. Yock Young Dan (NUS: National University of Singapore)H-Index: 24
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BACKGROUND Current guidelines have limited consensus on the approach to portal venous thrombosis (PVT) in cirrhotic patients. While there is rising interest in direct oral anticoagulants (DOACs) use for PVT, current evidence is limited by small sample size and lack of comparisons to traditional anticoagulants. Thus, a network meta-analysis was conducted to compare the use of DOACs with traditional anticoagulants. METHODS Medline and Embase were searched for articles about anticoagulation use in ...
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#1Yanyan Cao (HUST: Huazhong University of Science and Technology)H-Index: 2
#2Tao Ouyang (HUST: Huazhong University of Science and Technology)
Last. Chuansheng Zheng (HUST: Huazhong University of Science and Technology)H-Index: 15
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To investigate the efficacy of sequential apatinib treatment in patients with unresectable hepatocellular carcinoma (HCC) refractory to sorafenib–transarterial chemoembolization (TACE). This respective study was conducted on 95 consecutive patients with sorafenib–TACE-refractory unresectable HCC in our center from January 2014 to December 2019. According to the response to sorafenib–TACE treatment and the subsequent management, the eligible patients were assigned into three groups: sorafenib–TAC...
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#1Hye Won Lee (Yonsei University)H-Index: 22
Last. Park Sy
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#1Jee-Fu HuangH-Index: 34
Last. Ching-I Huang (KMU: Kaohsiung Medical University)H-Index: 14
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BACKGROUND The efficacy and safety of insulin sensitizer in Asians with non-alcoholic steatohepatitis (NASH) remain elusive. AIMS The double-blind, randomized, placebo-controlled trial was conducted aiming to investigate the efficacy and safety of pioglitazone in NASH patients. METHODS A total of 90 NASH patients (66 males, age = 44.1 ± 12.7 years) were prospectively randomized into oral pioglitazone 30 mg/day (Arm A) or placebo (Arm B) for 24 weeks. The primary endpoint was the efficacy of piog...
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#1Yi-Shin Huang (Taipei Veterans General Hospital)H-Index: 17
#2Ting-Tsung Chang (NCKU: National Cheng Kung University)H-Index: 59
Last. Yi-Hsiang Huang (Taipei Veterans General Hospital)H-Index: 52
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BACKGROUND AND AIMS Whether herbal and dietary supplements (HDS) are safer than Western conventional drugs is controversial. The aim of this study was to explore the characteristics and risk factors for HDS-induced liver injury (HILI) in Taiwan. METHODS This is a 9-year multi-center prospective study conducted in Taiwan from 2011 to 2019. Patients with HILI were compared to those with conventional drug-induced liver injury (CILI). RESULTS A total of 1,297 patients were enrolled, of whom 285 (22....
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#1Han Hu (Zunyi Medical College)H-Index: 2
#2Xinxin Hu (Zunyi Medical College)H-Index: 1
Last. Shide Lin (Zunyi Medical College)H-Index: 5
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BACKGROUND/PURPOSE Associations between the disturbances in glucose homeostasis and prognosis in patients with hepatitis B virus (HBV)-related acute-on-chronic liver failure (ACLF) remain unclear. This study was conducted to investigate the clinical characteristics of disturbances in glucose homeostasis and their associations with 90-day mortality in patients with HBV-related ACLF. METHODS Ninety-six patients with HBV-related ACLF without pre-existing diabetes were prospectively included. Glucos...
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#1Takanori Ito (Nagoya University)H-Index: 12
#2Masatoshi Ishigami (Nagoya University)H-Index: 29
Last. Satoshi YasudaH-Index: 50
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Background null The clinical course of liver injury induced by immune checkpoint inhibitors (ICIs) varies among individuals, and there were few reports on the therapeutic effects of corticosteroids based on the patterns of liver injury. null Methods null We evaluated the characteristics and clinical course of immune-related liver injury in 1214 patients treated with ICIs for advanced malignancies except for hepatocellular carcinoma between August 2014 and May 2021. null Results null During the f...
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#1Ming-Lun Yeh (KMU: Kaohsiung Medical University)H-Index: 19
#2Chao-Hung Hung (Memorial Hospital of South Bend)H-Index: 46
Last. Rong-Nan Chien (Memorial Hospital of South Bend)H-Index: 19
view all 39 authors...
BACKGROUND AND AIM The long-term outcome of hepatitis B virus (HBV) infection among patients dually infected with HBV and hepatitis C virus (HCV) remains unclear. We aimed to investigate the long-term liver outcomes of HBV/HCV-coinfected patients after antiviral therapy. METHODS A total of 11,359 chronically HCV-infected patients with interferon-based therapy were registered in a nationwide Taiwanese Chronic Hepatitis C Cohort. A propensity score matched (PSM) cohort of HCV mono-infected (n = 70...
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