Graefes Archive for Clinical and Experimental Ophthalmology
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#1Anyi Liang (Peking Union Medical College Hospital)H-Index: 2
#2Shanshan Jia (JNU: Jinan University)H-Index: 1
Last. Meifen Zhang (Peking Union Medical College Hospital)H-Index: 4
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PURPOSE Changes of choroidal circulation throughout the disease course of Vogt-Koyanagi-Harada (VKH) disease and the clinical significance remain unclear. Choriocapillary vascular density (CC VD) measured by optical coherence tomography angiography (OCTA) were compared in different disease stages of VKH and its correlation with other parameters was analyzed, aiming to explore their clinical relevance. METHODS This is a retrospective case series. One hundred and fourteen VKH patients and 47 norma...
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#1Efstathios Vounotrypidis (University of Ulm)
#2Sigrid Freissinger (LMU: Ludwig Maximilian University of Munich)H-Index: 2
Last. Armin Wolf (University of Ulm)H-Index: 1
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PURPOSE As the number of intravitreal injections (IVI) increases annually, this study aimed to assess the anatomical and functional outcomes following rhegmatogenous retinal detachment (RRD) surgery for IVI-associated RRD (IVARD). METHODS All non-vitrectomized eyes developing IVARD since 2007 in two European vitreoretinal centers (Department of Ophthalmology, LMU Munich, Germany, and Eye Clinic Luigi Sacco, University of Milan, Milan, Italy) were included. Main outcomes were primary and secondar...
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#1Edoardo Midena (UNIPD: University of Padua)H-Index: 39
#2Luisa Frizziero (UNIPD: University of Padua)H-Index: 10
Last. Elisabetta Pilotto (UNIPD: University of Padua)H-Index: 22
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This article aims to review the impact of detecting and quantifying intraocular biomarkers (liquid biopsy) in both aqueous and vitreous humor in eyes of people affected by diabetes mellitus. This is a detailed review about aqueous and/or vitreous humor sampling in human diabetic eyes for proteomic and/or metabolomic analysis contributing to the understanding of the pathophysiology and treatment effects of diabetic retinopathy. Aqueous and vitreous humor molecular biomarkers proved to be directly...
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#1Karthik Kumar (Aravind Eye Hospital)H-Index: 1
#2Sagnik Sen (Aravind Eye Hospital)H-Index: 6
Last. Kim Ramasamy (Aravind Eye Hospital)H-Index: 19
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BACKGROUND Photic retinopathy may lead to permanent foveal structural injury, leading to irreversible visual acuity loss. METHOD This prospective observational study evaluated 51 eyes of 30 patients with photic retinopathy. Optical coherence tomography (OCT) imaging was performed for all the eyes at baseline and final follow-up. All the eyes showed a focal outer retinal defect on spectral-domain OCT (SD-OCT) at the junction of the inner and outer photoreceptor segments. SD-OCT was used to measur...
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#1Ipek Cigdem Ucar (Istanbul Medeniyet University)
#2Fehim Esen (Istanbul Medeniyet University)H-Index: 10
Last. Veysel Aykut (Istanbul Medeniyet University)H-Index: 5
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Ocular discomfort is a common symptom in central sensitization syndromes. The aim of this study was to evaluate ocular surface discomfort and related corneal changes in patients with irritable bowel syndrome. Twenty-nine patients with IBS (20 female, 9 male, mean age: 45.3 ± 10.1 years) and 37 healthy control subjects (25 female, 12 male, mean age: 44.95 ± 9.76 years) were included. A detailed ophthalmological examination was performed to all participants including tear break-up time (TBUT) and ...
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PURPOSE Ferromagnetic foreign bodies (FFB) present during magnetic resonance imaging (MRI) explorations can lead to tissue injury due to movement, especially in and around the eyes. Ferromagnetic foreign bodies located in the intraocular area, eyelids, and orbit are thus prohibited from undergoing MRI. The aim of the study was to analyze movement of 4-mm ferromagnetic foreign bodies in MRI in the eye, eyelid, and orbit using computed tomography (CT) scan. METHOD We developed a porcine model usin...
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#1Annette K. Hoskin (USYD: University of Sydney)H-Index: 2
#2Rebecca Low (TTSH: Tan Tock Seng Hospital)
Last. Gangadhara SundarH-Index: 12
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PURPOSE To detail the methodology for a novel ocular trauma registry and utilize the registry to determine the demographics, nature of injury, and associations of severe visual loss for open globe injuries (OGI). METHODS Thirteen hospitals in 7 countries used International Globe and Adnexal Trauma Epidemiology Study (IGATES) platform. Patients presenting between April 2009 and 2020 with OGI (with or without) adnexal involvement or intraocular foreign body (IOFB) were included. RESULTS Analyses o...
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#1Mael Lever (University of Duisburg-Essen)H-Index: 1
#2Christian Halfwassen (University of Duisburg-Essen)H-Index: 1
Last. Michael R. R. Böhm (University of Duisburg-Essen)H-Index: 10
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PURPOSE A central diagnostic tool in adult glaucoma is the peripapillary retinal nerve fibre layer (pRNFL) thickness. It can be assessed by scanning laser polarimetry (SLP) or optical coherence tomography (OCT). However, studies investigating the relevance of pRNFL measurements in children are rare. This study aims to compare the glaucoma diagnosing ability of SLP and OCT pRNFL thickness measurements in a paediatric population. METHODS This retrospective study included 105 children (glaucoma: 22...
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PURPOSE To assess the long-term risk of geographic atrophy (GA) progression after cataract surgery. METHODS Subjects with GA secondary to AMD followed for at least 1 year with fundus autofluorescence imaging and with at least two visits at our centre were included. Patients with wet AMD, disciform scar, past history of intravitreal injections or laser treatment, other maculopathies and with poor quality images were excluded. GA area at baseline and at follow-up visit was measured. Three study gr...
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#1Tzukit Zehavi-Dorin (Sheba Medical Center)H-Index: 2
#2Nofar Nahum (TAU: Tel Aviv University)
Last. Hani Levkovitch-Verbin (Sheba Medical Center)H-Index: 14
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PURPOSE To investigate the relationship between exfoliation syndrome (XFS) and systemic diseases. METHODS A population-based, retrospective study with control group was conducted using the electronic medical database of Maccabi Health Services, the second largest Health Maintenance Organization (HMO) in Israel. Study population included Maccabi members from January 2003 to April 2016. Cases consisted of patients diagnosed with XFS regardless of glaucoma. The control group included Maccabi member...
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