Best Practice & Research in Clinical Obstetrics & Gynaecology
Papers 2261
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#1Nnabuike Chibuoke Ngene (University of the Witwatersrand)H-Index: 10
#2Jagidesa Moodley (UKZN: University of KwaZulu-Natal)H-Index: 22
Abstract null null Due to the disparity in resource availability between low- and high-resource settings, practice recommendations relevant to high-income countries are not always relevant, and often need to be adapted to low-resource settings. The adaptation applies to induction of labour (IOL) which is an obstetric procedure that deserves special attention because it involves the initiation of a process that requires regular and frequent monitoring of the mother and fetus by experienced health...
#1Harrison Banner (UWO: University of Western Ontario)
#2Rohan D'Souza (U of T: University of Toronto)H-Index: 16
Abstract null null Induction of labour is a two-step process involving cervical ripening and the initiation of uterine contractions, with the goal of achieving a vaginal birth. To optimize the chance of a safe and timely vaginal birth, the process of induction of labour should be evidence-based and individualized to the given person and situation. Here, we lay out a framework for how this should be done, emphasizing careful clinical assessment and planning, flexibility in the strategy of inducti...
#1Hsiu-Jung Tung (CGU: Chang Gung University)H-Index: 2
#2Huei-Jean Huang (CGU: Chang Gung University)H-Index: 10
Last. Chyong-Huey Lai (CGU: Chang Gung University)H-Index: 61
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Abstract null null Endometrial cancer (EC) usually presented as localized disease at diagnosis (67%), 20% of patients diagnosed with regional spread, and distant metastasis accounted for 9%. The standard treatments include hysterectomy, bilateral salpingo-oophorectomy, and pelvic with/without paraaortic lymph node dissection/biopsy. Adjuvant therapy would be arranged according to risk factors and stage. Risk group classification varied among different guidelines and studies and evolved with time...
#1Neerja Bhatla (AIIMS: All India Institute of Medical Sciences)H-Index: 25
#2Swati Tomar (AIIMS: All India Institute of Medical Sciences)
Last. Lalit Kumar (AIIMS: All India Institute of Medical Sciences)H-Index: 32
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Abstract null null Primary surgical management is successful as the sole therapeutic modality in the majority of women with early stage cervical, vaginal and vulvar cancer, but the presence of certain risk factors in the surgico-pathological specimen indicates a poorer prognosis. Adjuvant treatment can improve overall survival in such cases. Important risk factors in cervical cancer include intermediate-risk factors (large tumour size, deep cervical stromal invasion, lymph-vascular space invasio...
#1Aya El Helali (Li Ka Shing Faculty of Medicine, University of Hong Kong)
#2Gladys Shuk Tak Kwok (Li Ka Shing Faculty of Medicine, University of Hong Kong)
Last. Ka Yu Tse (Li Ka Shing Faculty of Medicine, University of Hong Kong)H-Index: 14
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Abstract null null Non-epithelial cancers arising from the ovary are uncommon malignancies. Germ cell tumors of the ovary arise from primordial germ cells, and sex cord-stromal tumors of the ovary represent a cluster of tumors arising from the sex cord and stromal compartment. Most patients diagnosed with germ cell tumors are young adults and adolescent females. Conversely, ovarian sex cord tumors are more common in a mature age group. null Advances in the adjuvant management of non-epithelial o...
#1Laura M.C. Vos (NKI-AVL: Netherlands Cancer Institute)
#2S. Lot Aronson (NKI-AVL: Netherlands Cancer Institute)
Last. Gabe S. Sonke (NKI-AVL: Netherlands Cancer Institute)H-Index: 39
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Abstract null null The long-term survival of advanced-stage ovarian cancer remains poor, despite extensive cytoreductive surgery, chemotherapy, and the recent addition of PARP inhibitors. Hyperthermic intraperitoneal chemotherapy (HIPEC) has shown survival benefit by specifically targeting peritoneal metastases, the primary site of disease recurrence. Various aspects of how HIPEC exerts its effect are incompletely understood. Improved understanding of the effects of hyperthermia on ovarian cance...
Abstract null null The mean duration of human pregnancy is 280 days but the range is wide, and “term” has been defined to range from 37 to 42 weeks. In the 18th and 19th centuries, labour induction was used mainly in cases of pelvic deformity, before the foetus grew too large to be delivered. Induction methods were unreliable until the 20th century, when pituitary extract, and then synthetic oxytocin and prostaglandins, became available. “Disproportion” was the leading indication for induction u...
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