Heart Failure Reviews
Papers 1,513
1 page of 152 pages (1,513 results)
#1Maya Guglin (IU: Indiana University)H-Index: 27
#2Kutaiba Nazif (IU: Indiana University)
A new onset acute heart failure (HF) with a sudden drop in the left ventricular ejection fraction (LVEF) post orthotopic liver transplant (LT) is a rare but a potentially fatal complication. Because in most of the cases there is no evidence of coronary thrombosis, it can be classified as nonischemic cardiomyopathy. More specifically, clinical presentation of this syndrome shares many features with stress-induced or takotsubo cardiomyopathy. The known factors that predispose these patients to acu...
#1Alberto Preda (UniSR: Vita-Salute San Raffaele University)H-Index: 1
#2Luca Liberale (UniGe: University of Genoa)H-Index: 21
Last. Fabrizio Montecucco (UniGe: University of Genoa)H-Index: 60
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Metabolic syndrome (MetS) includes different metabolic conditions (i.e. abdominal obesity, impaired glucose tolerance, hypertriglyceridemia, decreased HDL cholesterol, and/or hypertension) that concour in the development of cardiovascular disease and diabetes. MetS individuals often show adverse cardiac remodeling and myocardial dysfunction even in the absence of overt coronary artery disease or valvular affliction. Diastolic impairment and hypertrophy are hallmarks of MetS-related cardiac remod...
#1Pranav Chandrashekar (OHSU: Oregon Health & Science University)H-Index: 5
#2Anish K Desai (OHSU: Oregon Health & Science University)H-Index: 1
Last. Barry H. Trachtenberg (Houston Methodist Hospital)H-Index: 21
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The therapeutic landscape for cardiac amyloidosis is rapidly evolving. In the last decade, our focus has shifted from dealing with the inevitable complications of continued extracellular infiltration of amyloid fibrils to earlier identification of these patients with prompt initiation of targeted therapy to prevent further deposition. Although much of the focus on novel targeted therapies is within the realm of transthyretin amyloidosis, light chain amyloidosis has benefited due to an overlap pa...
#1Naushaba MohiuddinH-Index: 1
#2Stanley FrinakH-Index: 8
Last. Jerry YeeH-Index: 19
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Acute decompensated heart failure (ADHF) accounts for more than 1 million hospital admissions annually and is associated with high morbidity and mortality. Decongestion with removal of increased total body sodium and total body water are goals of treatment. Acute kidney injury (AKI) or chronic kidney disease (CKD) is present in two-thirds of patients with ADHF. The pathophysiology of ADHF and AKI is bidirectional and synergistic. AKI and CKD complicate the management of ADHF by decreasing diuret...
#1Chihiro Miyagi (Cleveland Clinic Lerner Research Institute)H-Index: 1
#2Takuma Miyamoto (Cleveland Clinic Lerner Research Institute)H-Index: 5
Last. Kiyotaka Fukamachi (Cleveland Clinic Lerner Research Institute)H-Index: 30
view all 6 authors...
Heart failure with preserved ejection fraction (HFpEF) is characterized by diastolic dysfunction and multiple comorbidities. The number of patients is continuously increasing, with no improvement in its unfavorable prognosis, and there is a strong need for novel treatments. New devices and drugs are difficult to assess at the translational preclinical step due to the lack of high-fidelity large animal models of HFpEF. In this review, we describe the summary of historical and evolving techniques ...
#1Alexander G. Hajduczok (Thomas Jefferson University)
#2Samer N Muallem (Penn State Milton S. Hershey Medical Center)H-Index: 1
Last. John P. Boehmer (Penn State Milton S. Hershey Medical Center)H-Index: 45
view all 5 authors...
Our recently published systematic review and meta-analysis of heart failure (HF) remote monitoring using implantable devices (Hajduczok et al. in HF Reviews 1-20, 1) has been updated to reflected new data from the GUIDE-HF trial (Lindenfeld et al. in Lancet 398(10304):991-1001, 2). Data from randomized controlled trials (RCTs) was assessed to determine the effectiveness of implantable remote monitoring on the improvement of outcomes in HF patients. With the inclusion of the data from 1000 patien...
#2Jean Michel Saad (Houston Methodist Hospital)
Last. Mouaz H. Al-Mallah (Houston Methodist Hospital)H-Index: 63
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Cardiac amyloidosis, characterized by progressive restrictive cardiomyopathy, presents unusual diagnostic challenges. Conventional cardiac scintigraphy has shown limited utility in the quantification of disease burden and serial follow-up of cardiac amyloidosis. The advent of specialized positron emission tomography with specific amyloid-binding radiotracers has the potential to change currently employed diagnostic algorithms for the imaging of cardiac amyloidosis. This review aims to discuss th...
Cardiac lymphangiogenesis plays an important physiological role in the regulation of interstitial fluid homeostasis, inflammatory, and immune responses. Impaired or excessive cardiac lymphatic remodeling and insufficient lymph drainage have been implicated in several cardiovascular diseases including atherosclerosis and myocardial infarction (MI). Although the molecular mechanisms underlying the regulation of functional lymphatics are not fully understood, the interplay between lymphangiogenesis...
#1Daniele Masarone (Leonardo)H-Index: 14
#2Roberta Pacileo (Leonardo)
Last. Giuseppe Pacileo (Leonardo)H-Index: 35
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Type 2 diabetes mellitus and heart failure are closely related, patients with type 2 diabetes mellitus have a higher risk of developing heart failure, and those with heart failure are at increased risk of developing type 2 diabetes. Although no specific randomized clinical trials have been conducted to test the effect of cardiovascular therapies (drugs and/or devices) in diabetic patients with heart failure, a lot of evidence shows that all interventions effective in improving prognosis in patie...
#1Caroline Verhestraeten (Novartis)H-Index: 1
#2Ward HeggermontH-Index: 14
Last. Michael Maris (Novartis)H-Index: 1
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Despite an enormous improvement in heart failure management during the last decades, the hospitalization and mortality rate of heart failure patients still remain very high. Clinical inertia, defined as the lack of treatment intensification in a patient not at evidence-based goals for care, is an important underlying cause. Clinical inertia is extensively described in hypertension and type 2 diabetes mellitus, but increasingly recognized in heart failure as well. Given the well-established guide...
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