Journal of Applied Toxicology
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#1Yi Hu (SJTU: Shanghai Jiao Tong University)H-Index: 8
#2Jingying Hu (Fudan University)H-Index: 1
Last. Ying Tian (SJTU: Shanghai Jiao Tong University)H-Index: 27
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Organophosphates (OPs) and pyrethroids (PYRs) are extensively used pesticides and often occur in the form of mixture, whereas little was known about their joint toxicities. We aim to investigate the individual and joint effects of OPs and PYRs exposure on zebrafish embryo by employing chlorpyrifos (CPF) and deltamethrin (DM) as representatives. Zebrafish embryos at 2 hours post fertilization (hpf) were exposed to CPF (4.80, 39.06, and 78.13 μg/L), DM exposure (0.06, 1.60, and 3.19 μg/L), and CPF...
2 CitationsSource
#1Kaori Miyaoku (Ridai: Tokyo University of Science)H-Index: 1
#2Yukiko Ogino (Kyushu University)H-Index: 25
Last. Shinichi Miyagawa (Ridai: Tokyo University of Science)H-Index: 28
view all 14 authors...
The G protein-coupled estrogen receptor 1 (Gper1) is a membrane-bound estrogen receptor that mediates non-genomic action of estrogens. A Gper1-mediating pathway has been implicated in reproductive activities in fish, including oocyte growth, but Gper1 has been characterized in only a very limited number of fish species. In this study, we cloned and characterized two genes encoding medaka (Oryzias latipes) Gper1s, namely, Gper1a and Gper1b, and phylogenic and synteny analyses suggest that these g...
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#1Agnieszka Czyżowska (UP: Pedagogical University)H-Index: 3
#2Anna Barbasz (UP: Pedagogical University)H-Index: 10
Zinc oxide nanoparticles (ZnO-NPs) are widely used in almost every area of life. Therefore, exposure to them is unavoidable, which makes it necessary to assess their safety for humans. This paper aims to determine toxicity of ZnO-NPs of two diameters toward human immune cells responsible for: innate response (U-937 and HL-60) and acquired response (COLO-720L and HUT-78). Mitochondrial activity, membrane integrity, degree of cellular lipid oxidation, induction of inflammation, and activation of t...
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#1Rogelio Recio-VegaH-Index: 8
Last. Mary Kay Amistadi (UA: University of Arizona)H-Index: 13
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Lung cancer is the most common neoplasm and the primary cause-related mortality in developed and in most of nondeveloped countries. Epidemiological studies have demonstrated that even at low arsenic doses, the lungs are one of the main target organs and that chronic arsenic exposure has been associated with an increase in lung cancer development. Among the risk factors for cancer, arsenic methylation efficiency (As3MT) and the clearance of arsenic from cells by two members of the ATP-binding cas...
1 CitationsSource
#1G. Castaldo (University of Antwerp)H-Index: 2
#1Giovanni Castaldo (University of Antwerp)
Last. Gudrun De Boeck (University of Antwerp)H-Index: 33
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To improve our understanding of underlying toxic mechanisms, it is important to evaluate differences in effects that a variety of metals exert at concentrations representing the same toxic level to the organism. Therefore, the main goal of the present study was to compare the effects of waterborne copper (Cu(II)), zinc (Zn(II)) and cadmium (Cd (II)) on a freshwater fish, the common carp (Cyprinus carpio), at concentrations being 0%, 25%, 50% and 100% of the 96 h LC50 (the concentration which is ...
3 CitationsSource
#1Sergio Raez-Villanueva (McMaster University)H-Index: 2
#2Genevieve A. Perono (McMaster University)H-Index: 2
Last. Alison C. Holloway (McMaster University)H-Index: 47
view all 5 authors...
Worldwide demand for petroleum products has resulted in increased oil and gas activities in many countries. Conventional and unconventional oil and gas extraction, production, and transport lead to increased levels of petroleum-derived polycyclic aromatic hydrocarbons (PAHs) in the environment. PAH exposure has profound effects on reproduction by affecting pathways involved in placental trophoblast cell function and impairing normal placental development and function-key contributors to reproduc...
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#1Rachel P. Frawley (NIH: National Institutes of Health)H-Index: 5
#2Dori R. Germolec (NIH: National Institutes of Health)H-Index: 63
Last. Kristen Ryan (NIH: National Institutes of Health)H-Index: 7
view all 10 authors...
Ionic liquids (ILs) are synthetic solvents used as replacements for volatile organic solvents. Human exposure occurs through dermal or oral routes. In rodents, several ILs were reported to induce dermal toxicity, irritation, and sensitization. Due to the potential for occupational exposure, and industrial use as nonvolatile solvents, 1-ethyl-3-methylimidazolium chloride (EMIM, 6.25% to 50% v/v), 1-butyl-3-methylimidazolium chloride (BMIM, 3.12% to 12.5% v/v), 1-butyl-1-methylpyrrolidinium chlori...
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#1Xinwen Zhang (UD: University of Delaware)
#2Delphis F. Levia (UD: University of Delaware)H-Index: 33
Last. Changqing Wu (UD: University of Delaware)H-Index: 18
view all 6 authors...
Lignin and lignin-based materials have received considerable attention in various fields due to their promise as sustainable feedstocks. Guaiacol (G) and syringol (S) are two primary monolignols that occur in different ratios for different plant species. As methoxyphenols, G and S have been targeted as atmospheric pollutants and their acute toxicity examined. However, there is a rare understanding of the toxicological properties on other endpoints and mixture effects of these monolignols. To fil...
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#1Nadia Kashetsky (St. John's University)
#2Rebecca M. Law (St. John's University)
Last. Howard I. Maibach (UCSF: University of California, San Francisco)H-Index: 135
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With the constant possibility of occupational exposures, chemical warfare, and targeted attacks, increased attention has been given to determining effective and timely dermal decontamination strategies. This systematic review summarises experimental studies reporting decontamination with water-based solutions of dermal chemical contaminants with in vivo human data. Embase, MEDLINE, PubMed, Web of Science, and Google Scholar databases were comprehensively searched using search terms ("cutaneous" ...
1 CitationsSource
#1Sonia Sanajou (EMU: Eastern Mediterranean University)H-Index: 1
#2Gönül Şahin (EMU: Eastern Mediterranean University)H-Index: 10
Last. Terken Baydar (Hacettepe University)H-Index: 15
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Usage of inorganic ingredients like aluminium salts in cosmetics and personal care products has been a concern for producers and consumers. Although aluminium is used to treat hyperhidrosis, some worries have been raised about aluminium's role in breast cancer, breast cyst and Alzheimer's disease. The human population is exposed to aluminium from vaccines, diet, and drinking water, but the frequent use of aluminium-based cosmetics might add additional local exposure. This paper reviews literatur...
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