Neural Regeneration Research
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#1Zhongqi Li (CUHK: The Chinese University of Hong Kong)H-Index: 4
#2Bonaventure Ip (CUHK: The Chinese University of Hong Kong)H-Index: 4
Last. Ho Ko (CUHK: The Chinese University of Hong Kong)H-Index: 14
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#1Gustavo de Bem Silveira (Unesc: Universidade do Extremo Sul Catarinense)H-Index: 6
#2Alexandre Pastoris Muller (Unesc: Universidade do Extremo Sul Catarinense)H-Index: 11
Last. Paulo Cesar Lock Silveira (Unesc: Universidade do Extremo Sul Catarinense)H-Index: 22
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#1Diane S. Nakamura (Montreal Neurological Institute and Hospital)H-Index: 4
#2Timothy E. Kennedy (Montreal Neurological Institute and Hospital)H-Index: 62
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#1Jia-Jia Wu (SHU: Shanghai University)H-Index: 4
#2Ye-Chen Lu (SJTU: Shanghai Jiao Tong University)
Last. Jian-Guang Xu (SHU: Shanghai University)H-Index: 12
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Facial synkinesis is a troublesome sequelae of facial nerve malfunction. It is difficult to recover from synkinesis, despite improved surgical techniques for isolating the peripheral facial nerve branches. Furthermore, it remains unclear whether long-term dysfunction of motor control can lead to irreversible plasticity-induced structural brain changes. This case-control study thus investigated the structural brain alterations associated with facial synkinesis. The study was conducted at Shanghai...
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#1Yang Wang (USTC: University of Science and Technology of China)H-Index: 2
#2Xiang-Qian Kong (SDU: Shandong University)
Last. Chaoshi Niu (USTC: University of Science and Technology of China)H-Index: 12
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The SOCS1/JAK2/STAT3 axis is strongly associated with tumor growth and progression, and participates in cytokine secretion in many diseases. However, the effects of the SOCS1/JAK2/STAT3 axis in experimental subarachnoid hemorrhage remain to be studied. A subarachnoid hemorrhage model was established in rats by infusing autologous blood into the optic chiasm pool. Some rats were first treated with JAK2/STAT3 small interfering RNA (Si-JAK2/Si-STAT3) or overexpression plasmids of JAK2/STAT3. In the...
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#1Matteo Haupt (GAU: University of Göttingen)H-Index: 2
#2Mathias Bähr (GAU: University of Göttingen)H-Index: 93
Last. Thorsten R. Doeppner (GAU: University of Göttingen)H-Index: 26
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Lithium has been used in the treatment of bipolar disorders for decades, but the exact mechanisms of action remain elusive to this day. Recent evidence suggests that lithium is critically involved in a variety of signaling pathways affecting apoptosis, inflammation, and neurogenesis, all of which contributing to the complex pathophysiology of various neurological diseases. As a matter of fact, preclinical work reports both acute and long-term neuroprotection in distinct neurological disease mode...
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#1Zhonghai Huang (JNU: Jinan University)H-Index: 2
#2Ai-Ying Feng (JNU: Jinan University)
Last. Panpan Yu (JNU: Jinan University)H-Index: 13
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Inhibitor of DNA binding 2 (Id2) can promote axonal regeneration after injury of the central nervous system. However, whether Id2 can promote axonal regeneration and functional recovery after peripheral nerve injury is currently unknown. In this study, we established a mouse model of bilateral sciatic nerve crush injury. Two weeks before injury, AAV9-Id2-3×Flag-GFP was injected stereotaxically into the bilateral ventral horn of lumbar spinal cord. Our results showed that Id2 was successfully del...
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#1Dawn Thean (HKU: University of Hong Kong)H-Index: 1
#2Alan S.L. Wong (HKU: University of Hong Kong)H-Index: 7
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#1Oscar McCook (University of Ulm)H-Index: 15
#2Angelika Scheuerle (University of Ulm)H-Index: 19
Last. Tamara Merz (University of Ulm)H-Index: 10
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In the porcine model discussed in this review, the acute subdural hematoma was induced by subdural injection of autologous blood over the left parietal cortex, which led to a transient elevation of the intracerebral pressure, measured by bilateral neuromonitoring. The hematoma-induced brain injury was associated with albumin extravasation, oxidative stress, reactive astrogliosis and microglial activation in the ipsilateral hemisphere. Further proteins and injury markers were validated to be used...
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Anatomy
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Spinal cord injury
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