Fems Microbiology Reviews
Papers 1493
1 page of 150 pages (1,493 results)
#1Ulrike Binsker (BfR: Federal Institute for Risk Assessment)
#2Annemarie Käsbohrer (University of Veterinary Medicine Vienna)H-Index: 29
Last. Jens A. Hammerl (BfR: Federal Institute for Risk Assessment)H-Index: 28
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The dramatic global rise of MDR and XDR Enterobacterales in human medicine forced clinicians to the reintroduction of colistin as last-resort drug. Meanwhile, colistin is used in the veterinary medicine since its discovery leading to a steadily increasing prevalence of resistant isolates in the livestock and meat-based food sector. Consequently, transmission of resistant isolates from animals to humans, acquisition via food, and exposure to colistin in the clinic are reasons for the increased pr...
#1Julia E Egido (UU: Utrecht University)
#2Ana Rita Costa (Kavli Institute of Nanoscience)H-Index: 20
Last. Stan J. J. Brouns (Kavli Institute of Nanoscience)H-Index: 40
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We are in the midst of a golden age of uncovering defense systems against bacteriophages. Apart from the fundamental interest in these defense systems, and revolutionary applications that have been derived from them (e.g. CRISPR-Cas9 and restriction endonucleases), it is unknown how defense systems contribute to resistance formation against bacteriophages in clinical settings. Bacteriophages are now being reconsidered as therapeutic agents against bacterial infections due the emergence of multid...
#1Virginie Rougeron (University of Montpellier)H-Index: 18
#2Larson BoundengaH-Index: 11
Last. Franck Prugnolle (University of Montpellier)H-Index: 9
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Malaria is considered one of the most important scourges that humanity has faced during its history, being responsible every year for numerous deaths worldwide. The disease is caused by protozoan parasites, among which two species are responsible of the majority of the burden, Plasmodium falciparum and Plasmodium vivax. For these two parasite species, the questions of their origin (how and when they appeared in humans), of their spread throughout the world, as well as how they have adapted to hu...
#1Joseph P. Receveur (MSU: Michigan State University)H-Index: 3
#2Alexandra Bauer (MSU: Michigan State University)
Last. Christine Chevillon (CNRS: Centre national de la recherche scientifique)H-Index: 32
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Understanding the interactions of ecosystems, humans and pathogens is important for disease risk estimation. This is particularly true for neglected and newly emerging diseases where modes and efficiencies of transmission leading to epidemics are not well understood. Using a model for other emerging diseases, the neglected tropical skin disease Buruli ulcer (BU), we systematically review the literature on transmission of the etiologic agent, Mycobacterium ulcerans (MU), within a One Health/EcoHe...
#1Henrik U. Stotz (University of Hertfordshire)H-Index: 23
#2Dominik Brotherton (University of Hertfordshire)H-Index: 1
Last. Jameel M. Inal (University of Hertfordshire)H-Index: 27
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Extracellular vesicles (EVs) are now understood to be ubiquitous mediators of cellular communication. In this review, we suggest that EVs have evolved into a highly regulated system of communication with complex functions including export of wastes, toxins and nutrients, targeted delivery of immune effectors, and vectors of RNA silencing. Eukaryotic EVs come in different shapes and sizes and have been classified according to their biogenesis and size distributions. Small EVs (sEVs or exosomes) a...
#1Miguel A. Matilla (CSIC: Spanish National Research Council)H-Index: 20
#2Félix Velando (CSIC: Spanish National Research Council)H-Index: 1
Last. Tino Krell (CSIC: Spanish National Research Council)H-Index: 40
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Bacteria have evolved many different signal transduction systems that sense signals and generate a variety of responses. Generally, most abundant are transcriptional regulators, sensor histidine kinases and chemoreceptors. Typically, these systems recognize their signal molecules with dedicated ligand-binding domains (LBDs), which, in turn, generate a molecular stimulus that modulates the activity of the output module. There are an enormous number of different LBDs that recognize a similarly div...
1 CitationsSource
#1Colin R. Harwood (Newcastle University)H-Index: 47
#2Yoshimi Kikuchi (Ajinomoto)H-Index: 14
Because the majority of bacterial species divide by binary fission, and do not have distinguishable somatic and germ-lines cells, they could be considered to be immortal. However, bacteria 'age' due to damage to vital cell components such as DNA and proteins. DNA damage can often be repaired using efficient DNA repair mechanisms. However, many proteins have a functional 'shelf life'; some short lived, others are relatively stable. Specific degradation processes are built into the life span of pr...
#1Rhastin A. D. Castro (University of Basel)H-Index: 1
#2Sonia Borrell (University of Basel)H-Index: 25
Last. Sebastien Gagneux (University of Basel)H-Index: 74
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Tuberculosis (TB) has been responsible for the greatest number of human deaths due to an infectious disease in general, and due to antimicrobial resistance (AMR) in particular. The etiological agents of human TB are a closely-related group of human-adapted bacteria that belong to the Mycobacterium tuberculosis complex (MTBC). Understanding how MTBC populations evolve within-host may allow for improved TB treatment and control strategies. In this Review, we highlight recent works that have shed l...
3 CitationsSource
#1Justyna Ruchala (Biotechnology Institute)H-Index: 7
#2Andriy A. Sibirny (Biotechnology Institute)H-Index: 30
Pentose sugars are widespread in nature and two of them, D-xylose and L-arabinose belong to the most abundant sugars being the second and third by abundance sugars in dry plant biomass (lignocellulose) and in general on planet. Therefore, it is not surprising that metabolism and bioconversion of these pentoses attract much attention. Several different pathways of D-xylose and L-arabinose catabolism in bacteria and yeasts are known. There are even more common and really ubiquitous though not so a...
3 CitationsSource
#1Hannah Jeckel (MPG: Max Planck Society)H-Index: 6
#2Knut Drescher (MPG: Max Planck Society)H-Index: 29
The cellular morphology and sub-cellular spatial structure critically influence the function of microbial cells. Similarly, the spatial arrangement of genotypes and phenotypes in microbial communities has important consequences for cooperation, competition, and community functions. Fluorescence microscopy techniques are widely used to measure spatial structure inside living cells and communities, which often results in large numbers of images that are difficult or impossible to analyze manually....
9 CitationsSource
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