Respiratory Medicine
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#1Berta Sáez-Giménez (Autonomous University of Barcelona)H-Index: 4
#2David Clofent (Autonomous University of Barcelona)H-Index: 1
Last. Victoria E. Ruiz (Autonomous University of Barcelona)H-Index: 9
view all 14 authors...
ABSTRACT null null Background null Venous thromboembolism (VTE) is a major complication after lung transplantation (LT). However, its pathophysiology remains unknown, and coagulation profiles have yet to be described. null null null Objective null The aim of this study was to longitudinally assess coagulation status after LT. null null null Methods null We performed a prospective study and described the coagulation profiles of 48 patients at 5 different time-points: before LT and at 24-72 hours,...
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#1Geertje M. de Boer (EUR: Erasmus University Rotterdam)H-Index: 4
Last. Rudi W. Hendriks (EUR: Erasmus University Rotterdam)H-Index: 54
view all 11 authors...
Abstract null null Introduction null Adult-onset asthma (AOA) is usually more severe compared to childhood onset asthma (CoA). Given the increasing evidence that AoA is associated with obesity, we investigated the relationship of other related metabolic comorbid conditions with AoA compared to CoA. null null null Study design and methods null This cross-sectional study compared the metabolic syndrome and lipid derived inflammatory markers in patients with AoA, CoA and age- and sex-matched contro...
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#1Tinne Goos (Katholieke Universiteit Leuven)H-Index: 1
#2Laurens J. De Sadeleer (Katholieke Universiteit Leuven)H-Index: 7
Last. Robin Vos (Katholieke Universiteit Leuven)H-Index: 40
view all 13 authors...
Abstract null null Randomized placebo-controlled trials demonstrated the efficacy of antifibrotic treatment in non-IPF progressive fibrosing ILD (fILD). Currently, there is no consensus on how progression should be defined and clinical data of non-IPF fILD patients in a real-world setting are scarce. null Non-IPF fILD patients presenting at the University Hospitals Leuven between 2012 and 2016 were included. Different definitions of progression according to the selection criteria of the INBUILD,...
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#1Carlo Arevalo (URMC: University of Rochester Medical Center)H-Index: 1
#2R. James White (URMC: University of Rochester Medical Center)H-Index: 20
Last. Daniel J. Lachant (URMC: University of Rochester Medical Center)H-Index: 5
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Abstract null null Background and objectives null Pulmonary hypertension is commonly seen in end stage kidney disease and is most commonly due to elevated left heart pressures. There is limited data about vasodilator use during the management of Group 1 pulmonary arterial hypertension in the context of those who also have or later developed end stage kidney disease. The objective of this study was to determine safety and efficacy of vasodilator therapy in precapillary pulmonary hypertension requ...
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#1Michela Abrami (UniTS: University of Trieste)H-Index: 12
#2Massimo Maschio (UniTS: University of Trieste)H-Index: 8
Last. Barbara RuaroH-Index: 17
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Abstract null null Background null As most cystic fibrosis (CF) patients progress to respiratory failure, lung functionality assessment is pivotal. We previously developed a test that indirectly monitors airways (inflammation/functional test) by measuring the spin-spin relaxation time (T2m) of the water hydrogens present in CF sputum. Here the T2m significance in the monitoring of CF lung disease was further investigated by studying the correlation of T2m with: 1) sputum viscoelasticity, 2) muco...
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#5Alicia K. Gerke (UI: University of Iowa)H-Index: 16
Abstract null null Introduction null Sarcoidosis is a rare inflammatory disease with unclear natural history. Using a large, retrospective, longitudinal, population-based cohort, we sought to define its natural history in order to guide future clinical studies. null null null Methods null We identified 722 newly diagnosed cases of sarcoidosis within Kaiser Permanente Northwest health care records between 1995 and 2015. We investigated immunosuppressive medication use in the two years following d...
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#1Paola Rogliani (University of Rome Tor Vergata)H-Index: 41
#2Beatrice Ludovica Ritondo (University of Rome Tor Vergata)H-Index: 5
Last. Luigino Calzetta (University of Parma)H-Index: 8
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Abstract null null Small airway disease is recognized as a cardinal pathological process of chronic obstructive pulmonary disease (COPD), and recently small airways have been recognized as a major site of airflow obstruction also in asthmatic patients. The transversal involvement of small airways in COPD and asthma has warranted research efforts to identify therapeutic strategies able to unlock the small airway compartment. The mainstay of COPD treatment is represented by long-acting β2-adrenoce...
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#2Nurdan Köktūrk (Gazi University)
Last. Hosam H. Masoud (Cairo University)
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Abstract null null Chronic obstructive pulmonary disease (COPD) has a significant impact on healthcare systems and health-related quality of life. Increased prevalence of smoking is an important factor contributing to high burden of COPD in the Middle East and Africa (MEA). Several other factors including sedentary lifestyle, urbanization, second-hand smoke, air pollution, and occupational exposure are also responsible for the upsurge of COPD in the MEA. Frequent COPD exacerbations accelerate di...
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#1Toby Capstick (Leeds Teaching Hospitals NHS Trust)H-Index: 4
#2Nooria F. Azeez (Leeds Teaching Hospitals NHS Trust)
Last. Ian Clifton (Leeds Teaching Hospitals NHS Trust)H-Index: 11
view all 6 authors...
Abstract null null Background null The management of asthma and COPD is largely dependent on patients being able to use their inhaled medication correctly, but poor inhaler technique continues to be a recurring theme in studies and clinical practice. This is associated with poor disease control, increased risk of exacerbations and hospital admissions, and so there is a need to redesign services for patients to optimise their medicines use. null null null Methods null A novel ward-based dedicated...
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BACKGROUND Severe eosinophilic asthma is a high-burden disease. Mepolizumab has been effective in several randomized clinical trials. However, such success might not be applicable to patients treated in usual clinical practice. The objectives of this article are to evaluate the efficacy of mepolizumab in severe uncontrolled eosinophilic asthma under usual clinical practice, and to determine characteristics associated with the response to this treatment. METHODS We have conducted a retrospective,...
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