Applied Microbiology and Biotechnology
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#1Qing-Bin Wu (ZJU: Zhejiang University)
#2Xin-Ai Chen (ZJU: Zhejiang University)H-Index: 6
Last. Yong-Quan Li (ZJU: Zhejiang University)H-Index: 15
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Genome sequencing has revealed that each Streptomyces contains a wide range of biosynthetic gene clusters (BGCs) and has the capability to produce more novel natural products than what is expected. However, most gene clusters for secondary metabolite biosynthesis are cryptic under normal growth conditions. In Streptomyces tsukubaensis, combining overexpression of the putative SARPs (Streptomyces antibiotic regulatory proteins) and bioactivity-guided screening, the silent gene cluster (tsu) was s...
#1Chuan Wang (SUSE: Sichuan University of Science and Engineering)H-Index: 1
#2Mou Wang (SUSE: Sichuan University of Science and Engineering)H-Index: 1
Last. Meng-Ping Zhang (SUSE: Sichuan University of Science and Engineering)H-Index: 1
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Ethyl carbamate (EC) is a genotoxic and carcinogenic compound that is also a by-product of fermented foods (bread, sour milk, soy cheese, etc.) and alcoholic beverages (wine, sake, distilled liquor, etc.). Studies have showed that ethyl carbamate is ingested by humans primarily through the consumption of alcoholic beverages. Many countries have thus established EC limits for alcoholic beverages. Chinese liquor (Baijiu) is a traditional and unique distilled liquor, which has a huge consumption in...
#1Guoqing Zhang (QUST: Qingdao University of Science and Technology)
#2Nan Zhang (QUST: Qingdao University of Science and Technology)H-Index: 2
Last. Huibin Zou (QUST: Qingdao University of Science and Technology)H-Index: 1
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Diversified members of hop bitter acids (α- and β-acids) have been found in hop (Humulus lupulus). Mixtures of hop bitter acids have been traditionally applied in brewing and food industries as bitterness flavors or food additives. Recent studies have discovered novel applications of hop bitter acids and their derivatives in medicinal and pharmaceutical fields. The increasing demands of purified hop bitter acid promoted biosynthesis efforts for the heterologous biosynthesis of objective hop bitt...
#1Kai Xia (ZJSU: Zhejiang Gongshang University)H-Index: 2
#2Jiawen Ma (ZJSU: Zhejiang Gongshang University)
Last. Xinle Liang (ZJSU: Zhejiang Gongshang University)H-Index: 7
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Acetic acid bacteria (AAB) are a group of Gram-negative and strictly aerobic microorganisms widely used in vinegar industry, especially the species belonging to the genera Acetobacter and Komagataeibacter. The environments inhabited by AAB during the vinegar fermentation, in particular those natural traditional bioprocesses, are complex and dynamically changed, usually accompanied by diverse microorganisms, bacteriophages, and the increasing acetic acid concentration. For this reason, how AAB su...
#1Ziqiu Lin (SCAU: South China Agricultural University)H-Index: 9
#2Shimei Pang (SCAU: South China Agricultural University)H-Index: 7
Last. Shaohua Chen (SCAU: South China Agricultural University)H-Index: 27
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The herbicide butachlor has been used in huge quantities worldwide, affecting various environmental systems. Butachlor residues have been detected in soil, water, and organisms, and have been shown to be toxic to these non-target organisms. This paper briefly summarizes the toxic effects of butachlor on aquatic and terrestrial animals, including humans, and proposes the necessity of its removal from the environment. Due to long-term exposure, some animals, plants, and microorganisms have develop...
#1Ornella M. Ontañon (CSIC: Spanish National Research Council)H-Index: 3
#2Soma Bedő (BME: Budapest University of Technology and Economics)H-Index: 1
Last. Csaba Fehér (BME: Budapest University of Technology and Economics)H-Index: 7
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One of the main distinguishing features of bacteria belonging to the Cellulomonas genus is their ability to secrete multiple polysaccharide degrading enzymes. However, their application in biomass deconstruction still constitutes a challenge. We addressed the optimisation of the xylanolytic activities in extracellular enzymatic extracts of Cellulomonas sp. B6 and Cellulomonas fimi B-402 for their subsequent application in lignocellulosic biomass hydrolysis by culture in several substrates. As de...
#1Yarui Cheng (HAU: Huazhong Agricultural University)
#2Tianyuan Zhang (HAU: Huazhong Agricultural University)
Last. Wenli Chen (HAU: Huazhong Agricultural University)H-Index: 25
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Iron is a common cofactor in biological processes such as respiration, photosynthesis, and nitrogen fixation. The genes isiC and isiD encode unknown proteins, and the growth of ΔisiC and ΔisiD mutants is inhibited under iron-deficient conditions. To study the regulatory mechanisms of IsiC and IsiD during iron starvation, we carried out transcriptome and metabolome sequencing. The Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis showed that the photosynthesis, nitrogen metabolism, and ABC ...
#1Nitish Joat (University of Adelaide)
#2Thi Thu Hao Van (RMIT: RMIT University)H-Index: 16
Last. Kapil K. Chousalkar (University of Adelaide)H-Index: 21
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Gut health has major implications for the general health of food-producing animals such as the layer birds used in the egg industry. In order to modulate gut microbiota for the benefit of gut health, an understanding of the dynamics and details of the development of gut microbiota is critical. The present study investigated the phylogenetic composition of the gut microbiota of a commercial layer flock raised in cages from hatch to the end of the production cycle. This study also aimed to underst...
#1Qiuxia Fan (NWAFU: Northwest A&F University)
#2Yahong Yuan (NWAFU: Northwest A&F University)H-Index: 24
Last. Tianli Yue (Northwest University (China))H-Index: 29
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Shigella flexneri (Sh. flexneri), a common foodborne pathogen, has become one of the main threats to food safety and human health due to its high pathogenicity and persistent infection. The objective of this study was to explore the antimicrobial and anti-biofilm activities and the possible mechanism of thymoquinone (TQ) against Sh. flexneri. The minimum inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of TQ against Sh. flexneri were 0.4 and 0.5 mg/mL, respectively. TQ...
#1Guangqi Li (NAU: Nanjing Agricultural University)H-Index: 3
Last. Ruifu Zhang (NAU: Nanjing Agricultural University)H-Index: 33
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Xylanases have a broad range of applications in industrial biotechnologies, which require the enzymes to resist the high-temperature environments. The majority of xylanases have maximum activity at moderate temperatures, which limited their potential applications in industries. In this study, a thermophilic GH10 family xylanase XynAF1 from the high-temperature composting strain Aspergillus fumigatus Z5 was characterized and engineered to further improve its thermostability. XynAF1 has the optima...
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Molecular biology