Pathology International
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Papers 6922
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#1Kyoko OnoH-Index: 2
#2Rika KasajimaH-Index: 3
Last. Tomoyuki YokoseH-Index: 36
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Endometrial neuroendocrine carcinoma is a rare disease with unknown clinicopathological and molecular characteristics. Therefore, we conducted the present study to elucidate the clinicopathological and molecular characteristics of endometrial neuroendocrine carcinoma, as compared to conventional endometrial carcinoma, and to determine the origin of the former. We analyzed 22 endometrial neuroendocrine carcinomas and 22 conventional endometrial neoplasia cases with respect to clinical, histologic...
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#1Masashi Akiya (JFCR: Japanese Foundation for Cancer Research)
#2Tomo Osako (JFCR: Japanese Foundation for Cancer Research)H-Index: 14
Last. Kengo Takeuchi (JFCR: Japanese Foundation for Cancer Research)H-Index: 50
view all 8 authors...
Myofibroblastoma is a rare benign mesenchymal tumor typically arising in the breast. We report a diagnostically challenging case of myofibroblastoma of the breast showing a rare palisaded morphology and an uncommon desmin- and CD34-negative immunophenotype. A 73-year-old man underwent an excision for an 8 mm-sized breast mass. Histology revealed that the tumor was composed of fascicles of bland spindle cells showing prominent nuclear palisading and Verocay-like bodies. First, schwannoma, maligna...
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#1Ashwin Akki (UF: University of Florida)H-Index: 9
#2Xiuli Liu (UF: University of Florida)H-Index: 8
Last. Ashwini K. Esnakula (The Ohio State University Wexner Medical Center)
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#1Takashi Tasaki (Kadai: Kagoshima University)H-Index: 4
#2Kazuhito Hatanaka (Tokai University)H-Index: 13
Last. Akihide Tanimoto (Kadai: Kagoshima University)H-Index: 34
view all 10 authors...
Sarcoidosis is a systemic granulomatous disease. In pulmonary sarcoidosis, granulomatous vascular involvement is a common feature that occurs in all types of vessels, including large elastic arteries to venules, but sarcoidosis complicated with pulmonary infarction has not been reported. We report a case of a 60 years old female, who was operated on a clinical diagnosis of lung cancer, and histological examination revealed a pulmonary infarction and sarcoidosis. In the pulmonary elastic arteries...
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#1Tadashi Sakane (Nagoya City University)H-Index: 5
#2Takayuki Murase (Nagoya City University)H-Index: 17
Last. Hiroshi Inagaki (Nagoya City University)H-Index: 40
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Cancer testis antigens (CTAs) are detected in cancer cells but not in healthy normal tissues, with the exception of gametogenic tissues. However, to our knowledge, expression of the antigens in thymic epithelial tumors has not been examined yet. We examined the immunohistochemical expression of five CTAs (MAGE-A, NY-ESO-1, MAGE-C1, SAGE and GAGE7) in 192 cases of thymic epithelial tumor. The CTAs were variably expressed in the thymic epithelial tumors. Type B component of type AB thymomas, type ...
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#1Satoko Mibayashi (Kyoto University)
#2Shinji Sumiyoshi (Kyoto University)H-Index: 14
Last. Hironori Haga (Kyoto University)H-Index: 49
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#1Satsuki Asai (Kyoto University)H-Index: 1
#2Shinji Sumiyoshi (Kyoto University)H-Index: 14
Last. Hironori Haga (Kyoto University)H-Index: 49
view all 7 authors...
Secretory carcinoma or mammary analog secretory carcinoma is an entity of salivary gland carcinoma that is characterized by the ETV6-NTRK3 gene fusion. Although it is generally considered to be a low-grade malignancy, some cases of secretory carcinoma with high-grade transformation (SCHG) have been reported. We herein describe a case of SCHG composed almost exclusively of the high-grade component. The patient presented with a growing mass in the buccal mucosa and underwent surgery. Tumor cells s...
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#1Yi-Ru Wu (KMU: Kaohsiung Medical University)
#2Yi-Chen Lee (KMU: Kaohsiung Medical University)H-Index: 3
Last. Hung-Lung Ke (KMU: Kaohsiung Medical University)H-Index: 17
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Upper tract urothelial carcinoma (UTUC) is a rare tumor with an incidence that varies greatly between Eastern and Western countries. Transaldolase 1 (TALDO1) is a rate-limiting enzyme of the pentose phosphate pathway. In humans, aberrant TALDO1 activity has been implicated in various autoimmune diseases and malignancies; however, the function of TALDO1 in UTUC has not been previously investigated. Here we evaluated the clinical significance of TALDO1 expression in 115 paraffin-embedded tumor sam...
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#1Shintaro Akabane (Hiroshima University)H-Index: 2
#2Naohide Oue (Hiroshima University)H-Index: 45
Last. Wataru Yasui (Hiroshima University)H-Index: 73
view all 14 authors...
Colorectal cancer (CRC) is the second leading cause of cancer-related mortality worldwide. Kinesin Family Member C1 (KIFC1) has been proposed as a promising therapeutic target due to its pivotal role in centrosome clustering to mediate cancer cell progression. This study aimed to analyze the expression and biological function of KIFC1 in CRC. Immunohistochemically, 67 (52%) of 129 CRC cases were positive for KIFC1 and statistically associated with poorer overall survival. KIFC1 small interfering...
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