Virus Genes
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#1Steven Van BormH-Index: 14
#2Mieke SteenselsH-Index: 7
Last. Bénédicte LambrechtH-Index: 25
view all 6 authors...
Infectious bronchitis virus (IBV, genus Gammacoronavirus) causes an economically important and highly contagious disease in chicken. Random primed RNA sequencing was applied to two IBV positive clinical samples and one in ovo-passaged virus. The virome of a cloacal swab pool was dominated by IBV (82% of viral reads) allowing de novo assembly of a GI-13 lineage complete genome with 99.95% nucleotide identity to vaccine strain 793B. In addition, substantial read counts (16% of viral reads) allowed...
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#1Ravendra P. Chauhan (UKZN: University of KwaZulu-Natal)H-Index: 6
#2Michelle Gordon (UKZN: University of KwaZulu-Natal)H-Index: 12
Genome sequences of eleven avian influenza virus (AIV) subtypes have been reported in swine populations from seven countries until August 2020. To unravel the transmission dynamics and spillover events of AIVs from avian reservoirs to swine, full-length hemagglutinin (HA) sequences of AIV subtypes (n = 11) reported from various avian species and swine were retrieved from the ‘Influenza Research Database’. Phylogenetic analysis identified closely related avian and swine AIV sequences suggesting p...
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#1Katharina Müller (LMU: Ludwig Maximilian University of Munich)H-Index: 10
#5Markus H. Antwerpen (LMU: Ludwig Maximilian University of Munich)H-Index: 1
Last. Heiner von Buttlar (LMU: Ludwig Maximilian University of Munich)
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SARS-CoV-2 infections elicit a humoral immune response capable of neutralising the virus. However, multiple variants have emerged with mutations in the spike protein amongst others, the key target of neutralising antibodies. We evaluated the neutralising efficacy of 89 serum samples from patients, infected with SARS-CoV-2 in the beginning of 2020, against two virus variants isolated from acutely infected patients and harbouring spike protein mutations. One isolate was assigned to lineage B.1.351...
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#1Suresh S Bandla (Manipal University)
#2Santhosha Devadiga (Manipal University)H-Index: 4
Last. Arunkumar Govindakarnavar (Manipal University)
view all 5 authors...
Respiratory syncytial virus (RSV) is a common cause of respiratory tract infections among children less than 5 years of age and the elderly. This study intended to determine the circulating genotypes of RSV among severe acute respiratory illness (SARI) cases during the period 2016–2018 in India, among hospitalized acute febrile illness cases of age ranging from 1 to 65 years. Throat/nasopharyngeal swab samples were subjected for testing RSV and subgroups by real-time reverse transcriptase polyme...
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#1Xupeng Wang (UH: University of Hawaii)H-Index: 1
#2Alejandro Olmedo-Velarde (UH: University of Hawaii)H-Index: 2
Last. Michael J. Melzer (UH: University of Hawaii)H-Index: 15
view all 10 authors...
The complete genome of a new umbra-like virus from edible fig (Ficus carica) was identified by high-throughput sequencing. Based on its similarity to umbra-like virus genome sequences available in GenBank, the proposed name of this new virus is "fig umbra-like virus" (FULV). The genome of full-length FULV-1 consists of 3049 nucleotides organized into three open reading frames (ORFs). Pairwise comparisons showed that the complete nucleotide sequence of the virus had the highest identity (71.3%) t...
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#1Xiuli Li (YZU: Yangzhou University)H-Index: 2
#2Shumiao Qiao (YZU: Yangzhou University)
Last. Jiao Hu (YZU: Yangzhou University)H-Index: 14
view all 15 authors...
H9N2 subtype avian influenza virus has dramatically evolved and undergone extensive reassortment since its emergence in early 1990s in China. The genotype S (G57), emerging in 2007 with the substitution of F98-like PB2 and M gene by G1-like ones, has become the overwhelming predominant genotype for the past 11 years since 2010. Here, we found that virus with G1-like PB2 were more efficient in protein expression and in infectious virus production than that with F98-like PB2 gene. By coinfected MD...
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#1Lu Lv (Peking Union Medical College)
#2Leiliang Zhang (Peking Union Medical College)H-Index: 25
Throughout the viral life cycle, interplays between cellular host factors and virus determine the infectious capacity of the virus. The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a great threat to human life and health. Extensive studies identified a number of host proviral and antiviral factors for SARS-CoV-2. In this review, we summarize the current understanding of the interplay between SARS-CoV-2 and cellular f...
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#1Renan de Souza Cascardo (UFV: Universidade Federal de Viçosa)H-Index: 4
#2Lorenna Leal Pires (Federal University of Piauí)
Last. José Evando Aguiar Beserra (Federal University of Piauí)H-Index: 7
view all 6 authors...
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#1Broňa Brejová (Comenius University in Bratislava)H-Index: 13
#2Boršová K (SAV: Slovak Academy of Sciences)H-Index: 2
Last. Tomáš Vinař (Comenius University in Bratislava)H-Index: 7
view all 10 authors...
SARS-CoV-2 mutants carrying the ∆H69/∆V70 deletion in the amino-terminal domain of the Spike protein emerged independently in at least six lineages of the virus (namely, B.1.1.7, B.1.1.298, B.1.160, B.1.177, B.1.258, B.1.375). We analyzed SARS-CoV-2 samples collected from various regions of Slovakia between November and December 2020 that were presumed to contain B.1.1.7 variant due to drop-out of the Spike gene target in an RT-qPCR test caused by this deletion. Sequencing of these samples revea...
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#1Ronald Tarigan (Nagoya University)H-Index: 1
#2Tetsufumi Katta (Nagoya University)
Last. Eiichi Hondo (Nagoya University)H-Index: 4
view all 7 authors...
Bats serve as natural hosts of Pteropine orthoreovirus (PRV), an emerging group of bat-borne, zoonotic viruses. Bats appear to possess unique innate immune system responses that can inhibit viral replication, thus reducing clinical symptoms. We examined the innate immune response against PRV and assessed viral replication in cell lines derived from four bat species (Miniopterus fuliginosus, Pteropus dasymallus, Rhinolophus ferrumequinum, and Rousettus leschenaultii), one rodent (Mesocricetous au...
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