Journal of Cardiac Failure
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#1David Liang (UCPH: University of Copenhagen)H-Index: 1
#2Elena Gardella (University of Southern Denmark)H-Index: 27
Last. Maurizio Sessa (UCPH: University of Copenhagen)H-Index: 13
view all 5 authors...
OBJECTIVE To compare the hazard for all-cause and heart failure (HF) mortality between valproate (VPA) and levetiracetam (LEV)/lamotrigine (LTG) users in older patients aged ≥65 with comorbidity of epilepsy and HF. METHODS Cohort study using Danish registers in the period from January 1996 until July 2018. The study population includes new users of LTG, LEV, or VPA. Cox regression model was used to compute crude and adjusted hazard ratios for the outcome using an intention-to-treat approach. Ave...
#1Muthiah Vaduganathan (Brigham and Women's Hospital)H-Index: 57
#2Gregg C. Fonarow (UCLA: University of California, Los Angeles)H-Index: 176
Last. Laine Thomas (Duke University)H-Index: 61
view all 13 authors...
ABSTRACT null null Background null Clinical practice guidelines support sustained use of renin-angiotensin-aldosterone-system (RAAS) inhibitors over time in heart failure with reduced ejection fraction, yet few data are available regarding frequency, timing, and predictors of early treatment discontinuation in clinical practice. null null null Methods null Among prevalent or new users of angiotensin-converting enzyme inhibitors (ACEi)/angiotensin receptor blockers (ARB), angiotensin receptor-nep...
#1Robert L. Owens (UCLA: University of California, Los Angeles)
#2Kade Birkeland (Cedars-Sinai Medical Center)H-Index: 5
Last. Raj M. Khandwalla (Cedars-Sinai Medical Center)H-Index: 5
view all 8 authors...
IMPORTANCE Heart failure and sleep disordered breathing have been increasingly recognized as co-occurring conditions. Their bidirectional relationship warrants investigation into whether heart failure therapy improves sleep and sleep disordered breathing. OBJECTIVE To explore the effect of treatment with sacubitril/valsartan on sleep-related endpoints from the AWAKE-HF study. DESIGN, SETTING, PARTICIPANTS, AND EXPOSURES AWAKE-HF was a randomized, double-blind study conducted in 23 centers in the...
#1Robert N. Sladen (Columbia University)H-Index: 21
#2Mark Shulman (Monash University)H-Index: 14
Last. Koji Takeda (Columbia University)H-Index: 26
view all 16 authors...
Abstract null null Background null : There is a paucity of data on depression, anxiety and post-traumatic stress disorder (PTSD) after left ventricular assist device (LVAD) implantation. We designed an observational study to integrate these with functional capacity and health-related quality of life (HR-QOL) in surviving LVAD patients. null null null Methods null : Consenting patients between one month and 9 years post-LVAD implantation (n = 121) were screened for functional capacity (WHO Disabi...
#1Jasmine A. Luzum (UM: University of Michigan)H-Index: 10
#2Ozioma Edokobi (UM: University of Michigan)
Last. David E. Lanfear (HFHS: Henry Ford Health System)H-Index: 31
view all 8 authors...
BACKGROUND It remains unclear whether there is a racial disparity in the response to angiotensin inhibitors in patients with heart failure with reduced ejection fraction (HFrEF), and the role of genomic ancestry. Therefore, we compared survival associated with angiotensin inhibitors in HFrEF patients by self-identified race and proportion of West African genomic ancestry. METHODS Three datasets totaling 1,153 and 1,480 self-identified Black and White HFrEF patients, respectively, were meta-analy...
#1Yu Hoshika (Nippon Medical School)H-Index: 1
#2Yoshiaki Kubota (Nippon Medical School)H-Index: 10
Last. Yayoi Tsukada (Nippon Medical School)H-Index: 8
view all 17 authors...
BACKGROUND Development of heart failure is associated with fluid balance, including that of extracellular water (ECW) and intracellular water (ICW). This study determined whether sodium-glucose cotransporter 2 (SGLT2) inhibitors affect fluid balance and improve heart failure in patients after acute myocardial infarction (AMI). METHODS EMBODY was a prospective, randomized, double-blinded, placebo-controlled trial of Japanese patients with AMI and type 2 diabetes. Overall, 55 patients who underwen...
#1John L. Jefferies (UTHSC: University of Tennessee Health Science Center)H-Index: 4
#2Maria V. DeVita (Lenox Hill Hospital)H-Index: 17
BACKGROUND Anxiety and depression may be under-recognized in patients with heart failure (HF). We therefore investigated the prevalence and temporal change of these symptoms in hospitalized patients with HF. METHODS AND RESULTS We prospectively evaluated consecutive hospitalized patients with HF using the Hospital Anxiety and Depression Scale (HADS) on admission and at discharge. The HADS-A (anxiety) and HADS-D (depression) scores were categorized as follows; 0-7: no symptoms, 8-10: mild, and 11...
#1Rahul ChaudharyH-Index: 10
#2Ajaypaul Sukhi (UNMC: University of Nebraska Medical Center)H-Index: 3
Last. John J. Pacella (University of Pittsburgh)H-Index: 13
view all 5 authors...
Introduction null Limited data are available on the use of internal jugular vein (IJV) ultrasound parameters to assess central venous pressure (CVP) and clinical outcomes among patients with suspected or confirmed heart failure (HF). null Methods null We performed electronic searches on PubMed, The Cochrane Library, EMBASE, EBSCO, Web of Science and CINAHL databases from the inception through January 9, 2021 to identify studies evaluating the accuracy and reliability of the IJV ultrasound parame...
#1Phillip H. Lam (Veterans Health Administration)H-Index: 10
#2Kalliopi Keramida (GW: George Washington University)
Last. Gaurav Choudhary (Brown University)H-Index: 25
view all 14 authors...
Background: A low right ventricular ejection fraction (RVEF) is a marker of poor outcomes in patients with heart failure with reduced ejection fraction (HFrEF). Beta-blockers improve outcomes in HFrEF, but whether this effect is modified by RVEF is unknown. Methods: Of the 2798 patients in Beta-Blocker Evaluation of Survival Trial (BEST), 2008 had data on baseline RVEF (mean, 35%; median, 34%). Patients were categorized into RVEF <35% (n=1012) and ≥35% (n=996). We estimated hazard ratio (HR) and...
Top fields of study
Intensive care medicine
Heart failure
Diabetes mellitus
Ejection fraction