Dermatologic Therapy
Papers 4,580
1 page of 458 pages (4,580 results)
#1Angelo Ruggiero (University of Naples Federico II)H-Index: 9
#2Gabriella Fabbrocini (University of Naples Federico II)H-Index: 44
Last. Matteo Megna (University of Naples Federico II)H-Index: 23
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IL-23-inhibitors, such as guselkumab and risankizumab, represent the newest class of biologics approved for psoriasis. Phase III trials have shown their efficacy and safety. However, real life data are still scant. to indirectly compare the effectiveness, safety and tolerability of guselkumab and risankizumab in real world practice. An Italian single-center retrospective cohort study enrolling moderate-to-severe psoriasis patients from September 1, 2018 and December 31, 2020 was performed to ind...
#1Mohammadreza Ghassemi (IUMS: Iran University of Medical Sciences)H-Index: 8
#2Masoumeh Roohaninasab (IUMS: Iran University of Medical Sciences)H-Index: 8
Last. Azadeh Goodarzi (IUMS: Iran University of Medical Sciences)H-Index: 11
view all 5 authors...
Macular amyloidosis (MA) is a common form of cutaneous amyloidosis that manifests as dark spots consisting of brown pigments with a rippled pattern on the skin, and the treatment of this condition is highly challenging. The aim of this study was to compare the efficacy and safety of intralesional injection of tranexamic acid (TXA) and topical application of Kligman combination drug in the treatment of macular amyloidosis. In this double-blind clinical trial, a total of 43 patients, who were diag...
#1Terri Shih (UCLA: University of California, Los Angeles)
#2Katrina Lee (UCLA: University of California, Los Angeles)H-Index: 1
Last. Jennifer L. Hsiao (USC: University of Southern California)
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Hyperhidrosis impairs quality of life (QOL) in hidradenitis suppurativa (HS) patients and may exacerbate HS. However, there is limited literature on whether hyperhidrosis treatments improve HS disease. To systematically review literature on efficacy and tolerability of hyperhidrosis treatments in HS patients. In May 2021, MEDLINE and EMBASE databases were systematically searched by two reviewers per PRISMA guidelines for articles on hyperhidrosis and HS. Sixteen articles met inclusion criteria (...
#1Wiebke Sondermann (University of Duisburg-Essen)H-Index: 13
#2Eva Hadaschik (University of Duisburg-Essen)H-Index: 6
view all 3 authors...
#1Nasrin Saki (SUMS: Shiraz University of Medical Sciences)H-Index: 7
#2Farzaneh Rahimi (SUMS: Shiraz University of Medical Sciences)
Last. Seyedeh Yasamin Parvar (SUMS: Shiraz University of Medical Sciences)
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Striae distensae (SD) are common skin conditions that have posed a significant challenge regarding their assessment and treatment. The present study aimed to evaluate the efficacy of microneedling in comparison to fractional CO2 laser therapy. Similar striae were selected and photographed. Each side was randomly assigned to be treated with CO2 fractional laser or microneedling four times at monthly intervals and followed up for 10 months. Outcome measures including the length and width of the la...
Drug induced bullous pemphigoid (DBP) associated to biologics administered for psoriasis is rare. DBP has been described especially in association with anti TNF-α drugs and anti IL12 and 23, but never in relation to guselkumab (anti IL23). We report the case of a 76-year-old male patient with severe psoriasis (PASI 20), presenting with generalized tense bullae and erosions after being recently switched to guselkumab therapy. Histology and direct immunofluorescence confirmed the suspect of bullou...
#1Massimo Dell'Antonia (University of Cagliari)H-Index: 1
#2Speranza Luisa Anedda (University of Cagliari)
Last. Caterina Ferreli (University of Cagliari)H-Index: 13
view all 5 authors...
#1Kevin PhanH-Index: 45
#2Shannon Younessi (MSSM: Icahn School of Medicine at Mount Sinai)
Last. Hooman Khorasani (MSSM: Icahn School of Medicine at Mount Sinai)H-Index: 8
view all 5 authors...
Botulinum toxin is a neurotoxic protein produced by Clostridium botulinum, the bacterium responsible for botulism. Botulinum toxin was first used for therapeutic indications in the 1970s for the treatment of strabismus. With greater understanding of its underlying physiology and safety profile, the use of botulinum toxin has now expanded to a range of cosmetic and medical indications. We performed a systematic review of current literature on the applications of botulinum toxin on off-label aesth...
#1Efstratios Vakirlis (Aristotle University of Thessaloniki)H-Index: 12
Last. Stamatios Gregoriou (National and Kapodistrian University of Athens)H-Index: 9
view all 3 authors...
A recently published systematic review and meta-analysis concludes that topical calcineurin inhibitors (TCIs) used in atopic dermatitis (AD) increase risk of lymphoma. We believe this study has weaknesses that have not been adequately addressed by the authors and its results must therefore be interpreted with caution. According to study results only pimecrolimus used for AD was statistically significantly associated with lymphoma, and not TCIs in general. Unclear participant baseline immunocompe...
#1Matteo Megna (University of Naples Federico II)H-Index: 23
#2Sonia Sofía Ocampo-Garza (University of Naples Federico II)H-Index: 4
Last. Elisa Camela (University of Naples Federico II)H-Index: 5
view all 6 authors...
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