BMC Endocrine Disorders
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Newest
#1Monireh Aziz (Shiraz University of Medical Sciences)
#2Yahya Jalilpiran (Tehran University of Medical Sciences)H-Index: 3
Last. Khadijeh Mirzaei (Tehran University of Medical Sciences)H-Index: 17
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BACKGROUND Several studies have investigated the association between dietary protein and the risk of diabetic nephropathy (DN); however, there is no agreement on the type of dietary protein sources that might increase the risk of DN. This study was conducted to investigate the associations between different protein sources and the odds of DN developing in Iranian women with existing type 2 diabetes. METHODS In this case-control study, 105 women with DN and 105 controls, matched for age and diabe...
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#1Ying Xue (Tongji University)H-Index: 1
#2Ran Li (Tongji University)H-Index: 2
Last. Yun Zhou (Tongji University)H-Index: 4
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BACKGROUND Sleeve gastrectomy (SG) is a profoundly effective operation for severe obese patients, but is closely associated with bone mass loss. Previous studies have reported changes of various serum factors which may be associated with bone mass loss after SG. However, those results are contradictory. In this study, we assessed the effects of SG on bone mass, microstructure of femurs, and changes in bone turnover markers (BTMs), serum adipokines, inflammatory factors and gastrointestinal hormo...
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#1Brice Touilloux (UNIL: University of Lausanne)H-Index: 1
#2Henri Lu (UNIL: University of Lausanne)
Last. Christel Tran (UNIL: University of Lausanne)H-Index: 12
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BACKGROUND The Mauriac syndrome was described in 1930 as a peculiar combination of poorly controlled diabetes mellitus type 1, stunted growth and glycogenic hepatopathy. More recently, lactic acidosis was recognized as an additional feature, often induced by insulin treatment. CASE PRESENTATION A 17-year old girl known for diabetes type 1A and Mauriac syndrome was admitted to the emergency room with hyperglycemia of > 41 mmol/l without ketoacidosis. Under a standard insulin regimen, hyperglycemi...
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#1Sorour Taheriniya (IUMS: Isfahan University of Medical Sciences)
#2Arman Arab (IUMS: Isfahan University of Medical Sciences)H-Index: 12
Last. Gholamreza Askari (IUMS: Isfahan University of Medical Sciences)H-Index: 26
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BACKGROUND The contribution of vitamin D to thyroid disorders has received paramount attention; however, results are mixed. Hence, we designed a systematic review and meta-analysis to obtain a definitive conclusion. METHODS The search included PubMed, ISI Web of Science, Scopus, and Google Scholar databases up to March 2021 to collect available papers reporting the relationship between serum levels of vitamin D and thyroid disorders. The pooled effect was reported as weighted mean difference (WM...
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#1Sadaf Alipour (Tehran University of Medical Sciences)H-Index: 9
#2Mahboubeh Abedi (Tehran University of Medical Sciences)
Last. Bita Eslami (Tehran University of Medical Sciences)H-Index: 12
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BACKGROUND Fibroadenoma (FA) is the most common benign solid breast mass in women, with no definite method of management. Because fibroadenoma is dependent on female sex hormones and comprises hypertrophic changes at cellular levels, we investigated the effects of metformin (MF), a safe hypoglycemic agent with anti-estrogenic and anti-proliferative properties, in the management of fibroadenoma. METHODS In this randomized clinical trial study, eligible women with fibroadenomas were assigned rando...
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#1Shimpei Iwata (Kurume University)H-Index: 3
#2Kenji Tsumura (Kurume University)
Last. Junichi Yasuda (Kurume University)
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Background null Thyroid stimulating hormone (TSH) receptor and local infiltrate lymphocytes have been considered as major pathological factors for developing thyroid-related ophthalmopathy. Overexpression of insulin-like growth factor-I (IGF-I) receptor has emerged as a promising therapeutic target for refractory patients. However, the relationship between activation of growth hormone (GH)/IGF-I receptor signaling and development or exacerbation of thyroid ophthalmopathy has not been elucidated....
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#1Ziyu Ren (CQMU: Chongqing Medical University)
Last. Wei Ren (CQMU: Chongqing Medical University)H-Index: 11
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Background null Wolfram syndrome (WFS) is a rare autosomal recessive genetic disease whose main cause is mutations in the WFS1 and CISD2 genes. Its characteristic clinical manifestations are diabetes insipidus, diabetes mellitus, optic atrophy and deafness. null Methods null In this study, two patients from this particular family underwent complete routine biochemical and ophthalmic tests. Blood, urine, routine stool test, visual acuity (VA) examination, visual field assessment, funduscope, opti...
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#1Nadia Sawicka-Gutaj (Poznan University of Medical Sciences)H-Index: 9
#2Waldemar Woźniak (Poznan University of Medical Sciences)H-Index: 4
Last. Marek Ruchała (Poznan University of Medical Sciences)H-Index: 22
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BACKGROUND Slipped capital femoral epiphysis (SCFE) is a hip disorder frequently occurring in adolescence. In adults it is rare and so far very few cases have been documented. CASE PRESENTATION This report presents a 25-year-old patient diagnosed with an anterior fossa giant chondroma, hypogonadotropic hypogonadism, and SCFE. The patient underwent surgical and hormonal therapy. His symptoms revealed, and he became a father. CONCLUSIONS Every patient diagnosed with SCFE in adulthood should underg...
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#1Shirleny Cardosa (QMUL: Queen Mary University of London)
#2B. William Ogunkolade (QMUL: Queen Mary University of London)
Last. Graham A. Hitman (QMUL: Queen Mary University of London)H-Index: 82
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BACKGROUND Betel-nut consumption is the fourth most common addictive habit globally and there is good evidence linking the habit to obesity, type 2 diabetes (T2D) and the metabolic syndrome. The aim of our pilot study was to identify gene expression relevant to obesity, T2D and the metabolic syndrome using a genome-wide transcriptomic approach in a human monocyte cell line incubated with arecoline and its nitrosated products. RESULTS The THP1 monocyte cell line was incubated separately with arec...
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#1Yoshiro Fushimi (Kawasaki Medical School)H-Index: 5
#2Shinji KameiH-Index: 4
Last. Tomoatsu Mune (Kawasaki Medical School)H-Index: 11
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BACKGROUND Multiple endocrine neoplasia type 1 (MEN1) is a syndrome characterized by pituitary neoplasia, primary hyperparathyroidism and pancreatic endocrine tumor. Here we show a case of MEN1 with a germline frameshift mutation in its gene accompanied by a giant cervical lipoma and multiple fatty deposits in the pancreas. CASE PRESENTATION A 28-year-old man noticed the decreased visual acuity of both eyes and visited our institution. Since he was diagnosed as visual disturbance and brain compu...
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