Translational Stroke Research
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Newest
#1Yinghua Jiang (Tulane University)H-Index: 8
#2Ning Liu (Tulane University)H-Index: 11
Last. Xiaoying Wang (Tulane University)H-Index: 3
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5 CitationsSource
#1Junxuan Lyu (University of Pittsburgh)H-Index: 1
#2Xiaoyan Jiang (University of Pittsburgh)H-Index: 13
Last. Jun Chen (University of Pittsburgh)H-Index: 152
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3 CitationsSource
#1Ruiqing Kang (LLU: Loma Linda University)H-Index: 2
#2Marcin Gamdzyk (LLU: Loma Linda University)H-Index: 4
Last. John H. Zhang (LLU: Loma Linda University)H-Index: 77
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2 CitationsSource
#1Fenghui Ye (UM: University of Michigan)H-Index: 1
#2Hugh J. L. Garton (UM: University of Michigan)H-Index: 33
Last. Guohua Xi (UM: University of Michigan)H-Index: 8
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2 CitationsSource
#1Sean N. Neifert (Mount Sinai Health System)H-Index: 4
#2Emily K. Chapman (Mount Sinai Health System)H-Index: 2
Last. R. Loch Macdonald (UCSF: University of California, San Francisco)H-Index: 2
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3 CitationsSource
#1Yiyang Li (UM: University of Macau)
#2Bowen Liu (Nanjing University of Chinese Medicine)
Last. Yonghua Zhao (UM: University of Macau)H-Index: 10
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Ischemic stroke (IS) accounts for most of the cases of stroke onset, and due to short therapeutic time window for thrombolysis and numerous limited treatment measures and contraindications, lots of patients cannot receive satisfying therapeutic effects resulting in high disability and mortality worldly. In recent years, extracellular vesicles (EVs), as nanosized membrane-structured vesicles secreted from almost all cells, especially from stem/progenitor cells, have been reported to exert signifi...
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Post-stroke vascular remodeling, including angiogenesis, facilitates functional recovery. Proper vascular repair is important for efficient post-stroke recovery; however, the underlying mechanisms coordinating the diverse signaling pathways involved in vascular remodeling remain largely unknown. Recently, axon guidance molecules were revealed as key players in injured vessel remodeling. One such molecule, Semaphorin 3E (Sema3E), and its receptor, Plexin-D1, control vascular development by regula...
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#1Yin-hong Cheng (HUST: Huazhong University of Science and Technology)
#2Yi-fan Jiang (HUST: Huazhong University of Science and Technology)
Last. Wen-sheng Qu (HUST: Huazhong University of Science and Technology)
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Galectin-1 is found in the vasculature and has been confirmed to promote angiogenesis in several cancer models. Furthermore, galectin-1 has been demonstrated to improve the recovery of cerebral ischemia. However, whether vascular remodeling contributes to this improvement is still unknown. In the present study, photochemical cerebral ischemia was induced in both galectin-1-treated (2 μg/day, i.c.v, 3 days) and galectin-1 knockout mice. Laser speckle imaging and immunofluorescent staining demonst...
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#1Lei-lei Mao (Peking Union Medical College)H-Index: 1
#1Leilei Mao (University of Pittsburgh)H-Index: 16
Last. Baoliang Sun (Peking Union Medical College)H-Index: 5
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Oxidative stress and neuroinflammatory response after the ischemic injury are important pathophysiologic mechanisms that cause brain tissue loss and neurological deficit. This study aims to observe the expression and role of carbonyl reductase 1 (CBR1), an NADPH-dependent oxidoreductase with specificity for carbonyl compounds such as 4-hydroxynonenal (4-HNE), in the brain after ischemic injury and to investigate the influence of CBR1 on ischemia-induced neuroinflammation. CBR1 expresses in the n...
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#1Ichiro Nakagawa (Nara Medical University)H-Index: 14
#2Hun-Soo Park (Nara Medical University)H-Index: 4
Last. Hiroyuki Nakase (Nara Medical University)H-Index: 24
view all 9 authors...
Cerebral hyperperfusion syndrome (CHS) is a serious complication following carotid artery stenting (CAS). Staged angioplasty (AP) could potentially prevent CHS and hyperperfusion phenomenon (HPP) after revascularization. However, methods for measuring the effects of staged AP on cerebral hemodynamic reserve have not been established. Here, we evaluated whether indocyanine green kinetics and near-infrared spectroscopy (ICG-NIRS) with hypocapnia induced by hyperventilation can detect the effects o...
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Top fields of study
Neurosurgery
Neurology
Anesthesia
Stroke
Ischemia
Diabetes mellitus
Medicine