Journal of Nutritional Biochemistry
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Papers 4179
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#1Cristiane dos Santos (UFSC: Universidade Federal de Santa Catarina)H-Index: 10
#2Julia Spanhol da Silva (UFSC: Universidade Federal de Santa Catarina)
Last. Alex Rafacho (UFSC: Universidade Federal de Santa Catarina)H-Index: 21
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Abstract We investigated whether combined long-term fructose and prednisolone intake would be more detrimental to the glucose homeostasis than if ingested separately. We also evaluated whether fish oil administration or interruption of treatments has any positive impact. For this, male adult Wistar rats ingested fructose (20%) (F) or prednisolone (12.5 µg/ml) (P) or both (FP) through drinking water for 12 weeks. A separate group of fructose and prednisolone-treated rats received fish oil treatme...
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#1Tanja Jankovic-Karasoulos (University of Adelaide)H-Index: 5
#2Dale McAninch (University of Adelaide)H-Index: 8
Last. Tina Bianco-Miotto (University of Adelaide)H-Index: 22
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Abstract Adequate Zinc (Zn) intake is required to prevent multiple teratogenic effects however deviations from adequate Zn intake, including high maternal Zn status, have been linked to increased incidence of pregnancy complications, including those associated with inadequate placentation. Using placental trophoblast HTR8/SVneo cells and first trimester human placental explants (n=12), we assessed the effects of varying Zn concentrations on trophoblast proliferation, viability, apoptosis and oxi...
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#1Shaniya Ahmad (DRDO: Defence Research and Development Organisation)
#2Shweta Arora (Jamia Millia Islamia)H-Index: 5
Last. Mansoor Ali Syed (Jamia Millia Islamia)H-Index: 17
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Abstract Vitamin D is customarily involved in maintaining bone and calcium homeostasis. However, contemporary studies have identified the implication of Vitamin D in several cellular processes including cellular proliferation, differentiation, wound healing, repair and regulatory systems inclusive of host defence, immunity and inflammation. Multiple studies have indicated co-relations between low serum levels of Vitamin D, perturbed pulmonary functions and enhanced incidences of inflammatory dis...
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#1Sin-Yu Chen (NTU: National Taiwan University)
#2Yi-Zhen Chen (NTU: National Taiwan University)
Last. Fu-Jung Lin (NTU: National Taiwan University)H-Index: 10
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Abstract Maternal hypercholesterolemia induces early onset of cardiovascular diseases in offspring; however, its underlying mechanism remains poorly understood. We hypothesized that maternal hypercholesterolemia increases offspring susceptibility to atherosclerosis in adulthood through developmental modifications of macrophages. Female apolipoprotein E (ApoE)-deficient mice were fed a Western-type diet (WD) or a control diet (CD) prior to and throughout gestation and lactation. The offspring wer...
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#1Shumao Ye (Tufts University)H-Index: 1
#2Nirupa R. Matthan (Tufts University)H-Index: 33
Last. Alice H. Lichtenstein (Tufts University)H-Index: 84
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Abstract Diet quality and statin therapy are established modulators of coronary artery disease (CAD) progression, but their effect on the gastrointestinal tract (GIT) and subsequent sequelae that could affect CAD progression are relatively unexplored. To address this gap, Ossabaw pigs (N = 32) were randomly assigned to receive isocaloric amounts of a Western-type diet (WD; high in saturated fat, refined carbohydrate, and cholesterol, and low in fiber) or a heart healthy-type diet (HHD; high in u...
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#1Xiao le Tang (HUST: Huazhong University of Science and Technology)
#2Xuan Wang (HUST: Huazhong University of Science and Technology)
Last. Shi yong Li (HUST: Huazhong University of Science and Technology)
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Abstract Sevoflurane, the most commonly used inhaled anesthetics in pediatric anesthesia, has been reported to induce cognitive impairment in developing brain in preclinical and clinical settings. However, the mechanism and therapeutic measures of this developmental neurotoxicity need to be further investigated. Resveratrol, a natural polyphenolic agent, has been reported to improve cognitive function in neurological disorders and aging models through anti-inflammatory activity. However, its eff...
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#1Richard S. Bruno (OSU: Ohio State University)H-Index: 35
#2Andrew P. Neilson (NCSU: North Carolina State University)H-Index: 5
Last. Naima Moustaid-Moussa (TTU: Texas Tech University)H-Index: 39
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#1Koji Ishida (Nara Medical University)H-Index: 2
#2Kosuke Kaji (Nara Medical University)H-Index: 18
Last. Hitoshi Yoshiji (Nara Medical University)H-Index: 43
view all 11 authors...
Abstract Alcoholic liver disease (ALD)-related fibrosis results from a variety of mechanisms including the accumulation of acetaldehyde, reactive oxygen species (ROS), and hepatic overload of endogenous lipopolysaccharide (LPS). Alcohol cessation is the therapeutic mainstay for patients with all stages of ALD, whereas pharmacological strategies for liver fibrosis have not been established. Sulforaphane, a phytochemical found in cruciferous vegetables, activates nuclear factor erythroid 2-related...
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#1Lei FangH-Index: 5
#2Michael RothH-Index: 51
Last. Ba Xuan Hoang (SC: University of Southern California)
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Abstract Asthma is characterised by chronic inflammation and tissue remodelling of the airways. Remodelling is resistant to pharmaceutical therapies. This study investigated the effect of zinc salicylate-methylsulfonylmethane (Zn-Sal-MSM) compared to zinc salicylate (Zn-Sal), or sodium salicylate (Na-Sal) or zinc chloride (ZnCl2) on remodelling parameters of human airway smooth muscle cells (ASMC). Human ASMC obtained from asthma patients (n=7) and non-asthma controls (n=7) were treated with one...
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#1Sara Sarroca (CSIC: Spanish National Research Council)H-Index: 6
#2Alaó Gatius (CSIC: Spanish National Research Council)H-Index: 1
Last. Rubén Corpas (CSIC: Spanish National Research Council)H-Index: 10
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Abstract Cumulative evidence indicates that excessive consumption of calories from saturated fat contributes to the development of Alzheimer's disease (AD). Here, we assess the triggering and progression of AD pathology induced by a high-fat diet (HFD), and the effects of resveratrol, a polyphenol found in common dietary sources with pleiotropic neuroprotective activities. Over 16 weeks, male wild type (WT) and AD transgenic 5XFAD mice were fed a control diet, HFD (60% kcal from fat), or HFD sup...
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