Journal of Nutritional Biochemistry
Papers 4,313
1 page of 432 pages (4,313 results)
#1Larissa Valadares Ramos (UnB: University of Brasília)
#2Teresa Helena Macedo da Costa (UnB: University of Brasília)H-Index: 18
Last. Sandra Fernandes Arruda (UnB: University of Brasília)H-Index: 17
view all 3 authors...
Abstract null null Coffee effects on glucose homeostasis in obesity remains controversial. We investigated whether coffee mitigates the negative effects on glucose metabolism induced by a high-fat diet and the interrelationships with redox-inflammatory responses. Rats were treated with: control (CT-); coffee (CT+) 3.9g of freeze-dried coffee/kg of diet; high-fat (HF-); or high-fat + coffee 3.9g of freeze-dried coffee/kg of diet (HF+) diet. The high-fat diet increased weight gain, feed efficiency...
#1Wanxiu Cao (Ocean University of China)H-Index: 4
#2Fang Liu (Ocean University of China)H-Index: 10
Last. Qingjuan Tang (Ocean University of China)H-Index: 24
view all 7 authors...
High-fat, high-sugar diet (HFHS) induced leptin resistance and intestinal epithelial dysfunction is implicated in hyperphagia and metabolic disorders. Numerous studies have demonstrated the efficacy of dietary interventions for reducing appetite. This study aims to investigate whether triacylglycerol rich in DHA (DHA-TG) could regulate appetite in mice fed with a HFHS diet and the mechanism by which it achieves that. DHA-TG could reduce food intake and regulate neuropeptides (POMC, AgRP, and NPY...
#1Changwon Yang (KU: Korea University)H-Index: 15
#2Sunwoo Park (Gyeongsang National University)H-Index: 18
Last. Whasun Lim (Kookmin University)H-Index: 24
view all 4 authors...
Palmitic acid (PA) induces apoptosis in the human trophoblast cell line HTR8/SVneo. However, the molecular mechanism underlying this effect remains unclear. Although small noncoding RNAs are involved in trophoblast growth and invasion during early pregnancy, the functional roles of tRNA-derived species are currently unknown. Therefore, the purpose of this study was to examine the involvement of tRNA-derived species in PA-induced apoptosis in human trophoblasts. In this study, we investigate the ...
#1Ying Zhao (HUST: Huazhong University of Science and Technology)H-Index: 2
#2Guibin Mei (HUST: Huazhong University of Science and Technology)H-Index: 2
Last. Ping Yao (HUST: Huazhong University of Science and Technology)H-Index: 33
view all 9 authors...
Abstract null null Emerging evidence has deemed vitamin D as a potential candidate for the intervention of type 2 diabetes (T2D). Herein, we explored the underlying mechanisms of T2D prevention by vitamin D, concentrating on pancreatic iron deposition reported recently. Zucker diabetic fatty (ZDF) rats were treated by vitamin D, with age-matched Zucker lean rats as control. As expected, vitamin D treatment for ZDF rats normalized islet morphology and β-cell function. Moreover, vitamin D alleviat...
#1Hua Wei (Fujian Medical University)H-Index: 1
#2Qi Ge (Fujian Medical University)
Last. Dali Zheng (Fujian Medical University)H-Index: 20
view all 7 authors...
Abstract null null Epigallocatechin-3-gallate (EGCG), the main active ingredient of green tea, exhibits low toxic side effect and versatile bioactivities, and its anti-cancer effect has been extensively studied. Most of the studies used cancer cell lines and xenograft models. However, whether EGCG can prevent tumor onset after cancer-associated mutations occur is still controversial. In the present study, Krt14-cre/ERT-Kras transgenic mice were developed and the expression of K-RasG12D was induc...
#1Kate Claycombe-Larson (ARS: Agricultural Research Service)H-Index: 3
#2Amy Bundy (ARS: Agricultural Research Service)H-Index: 2
Last. James N. Roemmich (ARS: Agricultural Research Service)H-Index: 13
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Abstract null null Maternal low-protein and postnatal high-fat (HF) diets program offspring obesity and type 2 diabetes mellitus (T2DM) risk by epigenetically reducing beige adipocytes (BA) via increased G9a protein expression (Histone3 Lysine9 dimethyl transferase), an inhibitor of the BA marker fibroblast growth factor 21 (FGF21). Conversely, offspring exercise reduces fat mass and white adipocytes, but the mechanisms are not yet understood. This work investigated whether exercise reduces offs...
#1Masaru Terasaki (HSUH: Health Sciences University of Hokkaido)H-Index: 10
#2Shion Ono (HSUH: Health Sciences University of Hokkaido)
Last. Michihiro Mutoh (Kyoto Prefectural University of Medicine)H-Index: 3
view all 10 authors...
Fucoxanthin (Fx) has shown potential cancer chemopreventive functions in a carcinogenic murine azoxymethane/dextran sodium sulfate (AOM/DSS) model. However, the molecular mechanisms based on transcriptome profiles in vivo remain poorly understood. We investigated Fx-dependent alterations of the transcriptome with cancer-associated proteins in colorectal mucosal tissue obtained from AOM/DSS mice with or without Fx treatment. Fx administration (50 mg/kg body weight for 14 weeks) significantly prev...
#1Yifei Bian (CAU: China Agricultural University)H-Index: 5
#2Jiaqi Lei (CAU: China Agricultural University)H-Index: 4
Last. Koichi Ito (UTokyo: University of Tokyo)H-Index: 2
view all 11 authors...
Kaempferol, a flavonoid identified in a wide variety of dietary sources, has been reported to possess anti-obesity properties; however, its underlying mechanism was poorly understood. Chronic, low-grade gut inflammation and dysbacteria are proposed as underlying factors as well as novel treatment approaches for obesity-associated pathologies. This present study aims to investigate the benefits of experimental treatment with kaempferol on intestinal inflammation and gut microbial balance in anima...
#1David Frankhouser (OSU: Ohio State University)H-Index: 11
#2Sarah A Steck (OSU: Ohio State University)H-Index: 3
Last. Lisa D. Yee (OSU: Ohio State University)H-Index: 31
view all 9 authors...
Abstract null null Omega-3 or n-3 polyunsaturated fatty acids (PUFAs) are widely studied for health benefits that may relate to anti-inflammatory activity. However, mechanisms mediating an anti-inflammatory response to n-3 PUFA intake are not fully understood. Of interest is the emerging role of fatty acids to impact DNA methylation (DNAm) and thereby modulate mediating inflammatory processes. In this pilot study, we investigated the impact of n-3 PUFA intake on DNAm in inflammation-related sign...
#1Sze Wing Ho (HKU: University of Hong Kong)H-Index: 2
#2Hani El-Nezami (HKU: University of Hong Kong)H-Index: 45
Last. Nagendra P. Shah (HKU: University of Hong Kong)H-Index: 81
view all 5 authors...
Inflammatory bowel disease (IBD) is a group of chronic inflammatory gastrointestinal diseases that causes worldwide suffering. Lactobacillus helveticus is a probiotic that can enhance intestinal barrier function via alleviation of excessive inflammatory response. Citrulline, a functional amino acid, has been reported to stimulate muscle synthesis and to function with a prebiotic-like action with certain Lactobacillus strains. The aim of this study was to investigate the potential synergistic eff...
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